One-year impact of COVID-19 pandemic on renal replacement therapy and kidney transplantation in a tertiary center in Southern Brazil.

Autor:	Teichmann PV; Hospital de Clínicas de Porto Alegre, Divisão de Nefrologia, Porto Alegre, RS, Brazil., Moschetta MO; Hospital de Clínicas de Porto Alegre, Divisão de Nefrologia, Porto Alegre, RS, Brazil.; Hospital de Clínicas de Porto Alegre, Divisão de Transplante, Porto Alegre, RS, Brazil., Franco RF; Hospital de Clínicas de Porto Alegre, Divisão de Nefrologia, Porto Alegre, RS, Brazil.; Hospital de Clínicas de Porto Alegre, Divisão de Transplante, Porto Alegre, RS, Brazil., Vicari AR; Hospital de Clínicas de Porto Alegre, Divisão de Nefrologia, Porto Alegre, RS, Brazil.; Hospital de Clínicas de Porto Alegre, Divisão de Transplante, Porto Alegre, RS, Brazil., Nunes GLS; Clínica de Hemodiálise Campo Bom, Campo Bom, RS, Brazil., Lazzaretti MAKN; Clínica do Rim de Alvorada, Alvorada, RS, Brazil., Gomes MG; Centro Nefrológico de Taquara, Taquara, RS, Brazil., Dorigoni SM; Clínica de Hemodiálise de São Leopoldo, São Leopoldo, RS, Brazil., Dall'Agnol PR; Fundação Hospitalar Santa Terezinha, Clínica Renal Erechim, Erechim, RS, Brazil., Klafke A; Hospital São Vicente de Paulo, Hemodiálise Osório, Osório, RS, Brazil., Thomé FS; Hospital de Clínicas de Porto Alegre, Divisão de Nefrologia, Porto Alegre, RS, Brazil.; Universidade Federal do Rio Grande do Sul, Faculdade de Medicina, Porto Alegre, RS, Brazil.; Instituto de Doenças Renais, Porto Alegre, RS, Brazil., Spuldaro F; Centro de Dialise e Transplante, Porto Alegre, RS, Brazil., Agra H; UNI-RIM, Clínica de Doenças Renais, Santa Cruz, RS, Brazil., Almeida R; Serviço de Nefrologia, Santa Casa de Pelotas, RS, Brazil., Lara DM; Hospital de Caridade de Carazinho, Centro de Nefrologia, Carazinho, RS, Brazil., Bauer AC; Hospital de Clínicas de Porto Alegre, Divisão de Nefrologia, Porto Alegre, RS, Brazil.; Hospital de Clínicas de Porto Alegre, Divisão de Transplante, Porto Alegre, RS, Brazil.; Universidade Federal do Rio Grande do Sul, Faculdade de Medicina, Porto Alegre, RS, Brazil., Karhol C; Hospital de Clínicas de Porto Alegre, Divisão de Nefrologia, Porto Alegre, RS, Brazil.; Hospital de Clínicas de Porto Alegre, Divisão de Transplante, Porto Alegre, RS, Brazil.; Universidade Federal do Rio Grande do Sul, Faculdade de Medicina, Porto Alegre, RS, Brazil.; Centro de Prevenção e Tratamento de Doenças Renais, Novo Hamburgo, RS, Brazil., Manfro RC; Hospital de Clínicas de Porto Alegre, Divisão de Nefrologia, Porto Alegre, RS, Brazil.; Hospital de Clínicas de Porto Alegre, Divisão de Transplante, Porto Alegre, RS, Brazil.; Universidade Federal do Rio Grande do Sul, Faculdade de Medicina, Porto Alegre, RS, Brazil.
Jazyk:	English; Portuguese
Zdroj:	Jornal brasileiro de nefrologia [J Bras Nefrol] 2023 Apr-Jun; Vol. 45 (2), pp. 210-217.
DOI:	10.1590/2175-8239-JBN-2022-0034en
Abstrakt:	Introduction: Patients on renal replacement therapy (RRT) and kidney transplant recipients (KTR) present multiple factors that may increase the risk of death from coronavirus disease 2019 (COVID-19). This study aimed to evaluate the incidence and impact of COVID-19 in RRT patients and KTRs. Methods: Between March 2020 and February 2021, we monitored the RRT population of thirteen dialysis facilities that refer patients for transplantation to our center, a tertiary hospital in Southern Brazil. In the same period, we also monitor COVID-19 incidence and mortality in our KTR population. Demographical, clinical, and COVID-19-related information were analyzed. Results: We evaluated 1545 patients in the dialysis centers, of which 267 (17.4%) were infected by COVID-19 and 53 (19.9%) died. Among 275 patients on the kidney transplant waiting list, 63 patients (22.9%) were infected and seven (11.1%) died. COVID-19 was the leading cause of death (29.2%) among patients on the waiting list. Within the population of 1360 KTR, 134 (9.85%) were diagnosed with COVID-19 and 20 (14.9%) died. The number of kidney transplants decreased by 56.7% compared with the same period in the previous twelve months. Conclusion: In the study period, patients on RRT and KTRs presented a high incidence of COVID-19 and high COVID-19-related lethality. The impact on the patients on the transplant waiting list was less pronounced. The lethality rate observed in both cohorts seems to be related to age, comorbidities, and disease severity.
Databáze:	MEDLINE
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