Endocrine-metabolic adaptations in Dorper ewes: comparison between single and twin pregnancies during gestation, parturition, and postpartum.

Autor: Santarosa BP; School of Veterinary Medicine and Animal Science (FMVZ), São Paulo State University (UNESP), Botucatu, São Paulo State, 18618-970, Brazil. biancasantarosavet@gmail.com.; Institute of Agricultural Sciences (ICA), Federal University of Jequitinhonha and Mucuri Valleys (UFVJM), Unaí, Minas Gerais State, 38610-000, Brazil. biancasantarosavet@gmail.com., Ferreira DOL; Secretary of Agriculture and Supply of São Paulo State, Bauru, São Paulo State, 17013-026, Brazil., Hooper HB; Department of Basic Sciences, School of Animal Science and Food Engineering (FZEA), University of São Paulo (USP), Pirassununga, São Paulo State, 13635-900, Brazil., Sinzato YK; Laboratory of Experimental Research On Gynecology and Obstetrics, Botucatu Medical School, São Paulo State University (UNESP), Botucatu, São Paulo State, 18618-970, Brazil., Damasceno DC; Laboratory of Experimental Research On Gynecology and Obstetrics, Botucatu Medical School, São Paulo State University (UNESP), Botucatu, São Paulo State, 18618-970, Brazil., Polizel DM; Department of Animal Science, 'Luiz de Queiroz' College of Agriculture (ESALQ), University of São Paulo, Piracicaba, São Paulo State, 13418-900, Brazil., Fioratti EG; Institute of Agricultural Sciences (ICA), Federal University of Jequitinhonha and Mucuri Valleys (UFVJM), Unaí, Minas Gerais State, 38610-000, Brazil., Dos Santos VH; Department of Veterinary Clinics, Londrina State University (UEL), Londrina, Paraná State, 86057-970, Brazil., da Silva AA; Department of Veterinary Medicine and Surgery, Federal Rural University of Rio de Janeiro (UFRRJ), Seropédica, Rio de Janeiro State, 23890-000, Brazil., Gonçalves RC; School of Veterinary Medicine and Animal Science (FMVZ), São Paulo State University (UNESP), Botucatu, São Paulo State, 18618-970, Brazil.
Jazyk: angličtina
Zdroj: Tropical animal health and production [Trop Anim Health Prod] 2022 Sep 16; Vol. 54 (5), pp. 307. Date of Electronic Publication: 2022 Sep 16.
DOI: 10.1007/s11250-022-03306-4
Abstrakt: The experiment was conducted at Araí & Zumbi farm on sixty healthy Dorper ewes to compare blood glucose, hormonal profile, and insulin resistance evaluation in sheep from conception until 48 h postpartum in single and twin pregnancies. All experimental ewes raised under semi-intensive management system. Sixty animals were selected from 150 estrous synchronized and pregnant ewes. The animals were divided into two groups based on single (G1, n = 30) and twin pregnancies (G2, n = 30). Blood samples were collected at nine time points: immediately after fixed-time artificial insemination (D0); at 30 days (D30), 90 days (D90), 120 days (D120), 130 days (D130), and 140 days (D140) of pregnancy; on the delivery day (DD); and at 24 h (PD1) and 48 h (PD2) postpartum. The results of blood glucose, insulin, glucagon, cortisol, and thyroid hormones (T3 and T4) levels showed significant differences over the analyzed sample times; however, only cortisol showed differences within groups, with the G1 having higher values than the G2 group. The interaction of the groups × nine sample times showed a significant result (P = 0.001) only for glucagon. The number of fetuses directly interfered with the glucagon profile throughout gestation. The glucose, cortisol, glucagon, and the homeostatic model assessment for insulin resistance (HOMA IR) concentrations increased at DD and decreased at PD1 and PD2. T3 and T4 showed different behaviors among the sample times. T3 values presented a decrease from D0 to D90, followed by an increase from D90 to DD. Otherwise, for T4 values, a decrease from D90 to D130 was observed, followed by an increase from D130 to D140. Despite the changes found in the endocrine system and metabolism in Dorper ewes throughout pregnancy, the nutritional management ensured a healthy status during pregnancy, delivery, and postpartum in single and twin gestation, whose HOMA IR profiles remained identical.
(© 2022. The Author(s), under exclusive licence to Springer Nature B.V.)
Databáze: MEDLINE
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