Diagnosing Torsades De Pointes Based on Correlation to QT Interval: A Systematic Review.

Autor:	Kahlon SS; Internal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA., Sikandar R; Internal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA., Tejovath S; Internal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA., Nair S; Internal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA., Hassan D; Epidemiology and Public Health, Ministry of Public Health, Doha, QAT.; Cardiology, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA., K Patel K; Internal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA., Peddemul A; Obstetrics and Gynecology, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA., Mostafa JA; Internal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2022 Aug 09; Vol. 14 (8), pp. e27833. Date of Electronic Publication: 2022 Aug 09 (Print Publication: 2022).
DOI:	10.7759/cureus.27833
Abstrakt:	Torsades de Pointes (TdP) is a rare form of tachyarrhythmia which can potentially be fatal due to its tendency to degenerate into ventricular fibrillation. It is described as a polymorphic ventricular tachycardia characterized by twisting of the QRS complexes around the electrocardiogram (ECG) baseline in patients with a prolonged QT interval. Prolonged QT interval is known as long QT syndrome. Torsades de Poccurs most commonly in patients with an extended QT interval duration, and even though monitoring an ECG can assist in its prevention, there is no defined duration of a QT interval that can lead to an increased risk of Torsades de Pointes. So, it is hard to determine what QT interval constitutes enough risk for Torsades de Pointes to require intervention. The QT interval duration also depends on other factors, namely heart rate (HR) and other factors such as drugs, congenital diseases, and a combination of both. In this study, we considered various causes of QT prolongation but mainly focused on congenital diseases, drugs, or perioperative risk of QT prolongation and the correlation with the risk of impending TdP. By following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and researching studies on various databases, namely PubMed, Science Direct, Medline, and CiNii we were able to find various systematic reviews and articles showing the association between prolonged QT interval and its degeneration into TdP. This review encourages further research into this topic to understand the implications of QT prolongation and how it can help save the lives of patients with known long QT syndrome, or those on QT prolonging drugs with simple ECG monitoring and treatment for the respective cause. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2022, Kahlon et al.)
Databáze:	MEDLINE
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