Hyperhemolytic Crisis Following Transfusion in Sickle Cell Disease With Acute Hepatic Crisis: A Case Report.

Autor: Trivedi K; Internal Medicine, Saint Michael's Medical Center, Newark, USA., Abbas A; Internal Medicine, Saint Michael's Medical Center, Newark, USA., Kazmi R; Internal Medicine, Saint Michael's Medical Center, Newark, USA., Shaaban H; Hematology/Oncology, Saint Michael's Medical Center, Newark, USA., Miller R; Pulmonary and Critical Care Medicine, Saint Michael's Medical Center, Newark, USA.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2022 Aug 10; Vol. 14 (8), pp. e27844. Date of Electronic Publication: 2022 Aug 10 (Print Publication: 2022).
DOI: 10.7759/cureus.27844
Abstrakt: Hyperhemolysis syndrome (HHS) is a catastrophic unpredictable consequence of blood transfusion in sickle cell disease. It leads to further drop in hemoglobin via immune mechanisms complicating a hospital course and prolonging length of stay. Although sickle cell patients receive multiple transfusions throughout their disease course, this condition remains underreported by health care professionals or misinterpreted for other sickle cell crises. We present a similar case highlighting the importance of early recognition of HHS and judicious blood transfusion in sickle cell disease patients to avoid such a complication.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2022, Trivedi et al.)
Databáze: MEDLINE