Advances in nanomaterial-based immunosensors for prostate cancer screening.

Autor: Khan R; Neurology Laboratory, National University of Science and Technology, Islamabad PC 051, Pakistan., Arshad F; Department of Mathematics and Sciences, College of Arts and Applied Sciences, Dhofar University, Salalah PC 211, Oman., Hassan IU; College of Engineering, Dhofar University, Salalah PC 211, Oman., Naikoo GA; Department of Mathematics and Sciences, College of Arts and Applied Sciences, Dhofar University, Salalah PC 211, Oman. Electronic address: gahmed@du.edu.om., Pedram MZ; Faculty of Mechanical Engineering-Energy Division, K.N. Toosi University of Technology, Tehran, Iran; Department of Analytical Chemistry, University of Kashan, Kashan, Iran. Electronic address: mona.zpedram@gmail.com., Zedegan MS; Faculty of Mechanical Engineering-Energy Division, K.N. Toosi University of Technology, Tehran, Iran; Department of Analytical Chemistry, University of Kashan, Kashan, Iran., Pourfarzad H; Center of excellence in electrochemistry, faculty of chemistry, University of Tehran, Tehran, Iran., Aljabali AAA; Faculty of Pharmacy, Department of Pharmaceutics and Pharmaceutical Technology, Yarmouk University, P. O. BOX 566, Irbid 21163, Jordan., Serrano-Aroca Á; Biomaterials and Bioengineering Lab., Centro de Investigación Traslacional San Alberto Magno, Universidad Católica de Valencia San Vicente Mártir, 46001 Valencia, Spain., Haggag Y; Department of Pharmaceutical Technology, Faculty of Pharmacy, Tanta University, Tanta 31512, Egypt., Mishra V; School of Pharmaceutical Sciences, Lovely Professional University, Phagwara 144411, India., Mishra Y; Department of Zoology, School of Bioengineering and Biosciences, Lovely Professional University, Phagwara 144411 (Punjab), India., Birkett M; Department of Mechanical and Construction Engineering, Northumbria University, Newcastle upon Tyne NE1 8ST, UK., Tambuwala MM; School of Pharmacy and Pharmaceutical Science, Ulster University, Coleraine County Londonderry BT52 1SA, Northern Ireland, UK. Electronic address: m.tambuwala@ulster.ac.uk.
Jazyk: angličtina
Zdroj: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2022 Nov; Vol. 155, pp. 113649. Date of Electronic Publication: 2022 Sep 13.
DOI: 10.1016/j.biopha.2022.113649
Abstrakt: Prostate cancer is one of the most common health hazards for men worldwide, specifically in Western countries. Rapid prostate cancer screening by analyzing the prostate-specific antigen present in male serum has brought about a sharp decline in the mortality index of this disease. Immunoassay technology quantifies the target analyte in the sample using the antigen-antibody reaction. Immunoassays are now pivotal in disease diagnostics, drug monitoring, and pharmacokinetics. Recently, immunosensors have gained momentum in delivering better results with high specificity and lower limit of detection (LOD). Nanomaterials like gold, silver, and copper exhibit numerous exceptional features and their use in developing immunosensors have garnered excellent results in the diagnostic field. This review highlights the recent and different immunoassay techniques used to detect prostate-specific antigens and discusses the advances in nanomaterial-based immunosensors to detect prostate cancer efficiently. The review also explores the importance of specific biomarkers and nanomaterials-based biosensors with good selectivity and sensitivity to prostate cancer.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2022 The Authors. Published by Elsevier Masson SAS.. All rights reserved.)
Databáze: MEDLINE
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