Primary Angiitis of the Central Nervous System: An Uncommon Cause of Stroke in the Young.
| Autor: | Thekkekarott Kuruvila A; Hospital Medicine, Asante Rogue Regional Medical Center, Medford, USA., Ranawat N; Neurology, Asante Rogue Regional Medical Center, Medford, USA., Hegde N; Anaesthesia, A J Institute of Medical Sciences, Mangalore, IND., Arora A; Internal Medicine, Aurora Medical Centre Bay Area, Marinette, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2022 Aug 08; Vol. 14 (8), pp. e27799. Date of Electronic Publication: 2022 Aug 08 (Print Publication: 2022). |
| DOI: | 10.7759/cureus.27799 |
| Abstrakt: | Primary angiitis of the central nervous system (PACNS) usually presents with symptoms of headache, cognitive impairment, or stroke with a mean age of onset at 50 years. Inflammation of the cerebral vessels can cause narrowing, occlusion, or thrombosis resulting in tissue ischemia and necrosis of the involved vessel territory. Findings can be seen on Magnetic Resonance Imaging (MRI) scans of the brain and serological markers of inflammation are typically within normal limits. The nonspecificity of PACNS presents a challenge for accurate diagnosis and must be differentiated from secondary vasculitis and Reversible Cerebral Vasoconstriction Syndrome (RCVS). Cerebral angiography, even though having low sensitivity and specificity, could sometimes be the only diagnostic tool available. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2022, Thekkekarott Kuruvila et al.) |
| Databáze: | MEDLINE |
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