| Autor: |
Shi H; Department of Anesthesia and Intensive Care Medicine, East Hospital Affiliated to Tongji University, Shanghai 200120, Shanghai, China.; Shanghai East Hospital, Dalian Medical University, Shanghai 200120, Shanghai, China. Corresponding author: Liao Lijun, Email: liao@pan-support.com., Hou Q; Department of Anesthesia and Intensive Care Medicine, East Hospital Affiliated to Tongji University, Shanghai 200120, Shanghai, China.; Shanghai East Hospital, Dalian Medical University, Shanghai 200120, Shanghai, China. Corresponding author: Liao Lijun, Email: liao@pan-support.com., Liao L; Department of Anesthesia and Intensive Care Medicine, East Hospital Affiliated to Tongji University, Shanghai 200120, Shanghai, China. |
| Abstrakt: |
Sepsis is a life-threatening organ dysfunction caused by an uncontrolled host response to infection. The mechanism of sepsis is extremely complicated and the mortality is still high. Persistent researches provide an important way to break through the "bottleneck" of clinical diagnosis and treatment of sepsis. In recent years, more and more studies have shown that gut-liver axis disorders, especially those caused by intestinal dysbiosis, intestinal barrier dysfunction, abnormal liver immune function, and bile acid metabolism disorders, play an important role in the occurrence and development of sepsis. This review describes the research progress of gut-liver axis disorders in the pathogenesis of sepsis for providing new ideas for clinical treatment. |
