NTRK3 mutation in secretory carcinoma of the parotid gland: A Case report.

Autor: AlKaabba F; Department of Medicine University of Maryland Medical Center Baltimore MD USA., Alloghbi A; College of Medicine King Khalid University Abha Saudi Arabia.; Department of Oncology Karmanos Cancer Institute, Wayne State University Detroit Michigan USA., Deajim Y; College of Medicine King Khalid University Abha Saudi Arabia., Sukkari MW; Faculty of Medicine University of Aleppo Aleppo Syria., Khan MYA; Department of Pathology, Detroit Medical Center Wayne State University Detroit Michigan USA., Sukari A; Department of Oncology Karmanos Cancer Institute, Wayne State University Detroit Michigan USA.
Jazyk: angličtina
Zdroj: Clinical case reports [Clin Case Rep] 2022 Sep 05; Vol. 10 (9), pp. e6243. Date of Electronic Publication: 2022 Sep 05 (Print Publication: 2022).
DOI: 10.1002/ccr3.6243
Abstrakt: Mammary analog secretory carcinoma (MASC) is a newly described carcinoma with a molecular hallmark of ETV6-NTRK3 fusion that promotes oncogenesis. While MASC histopathology was well-studied in the literature, clinical behavior remains unstudied. We present a 22-year-old man with painless parotid mass, which was diagnosed as salivary gland cancer, MASC subtype.
Competing Interests: None.
(© 2022 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
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