Current intraoperative storage and handling practices of autologous bypass conduit: A survey of the royal australasian college of surgeons.

Autor:	Haymet AB; Department of Vascular Surgery, The Royal Brisbane and Women's Hospital, Herston, QLD, Australia.; Critical Care Research Group, The Prince Charles Hospital, Chermside, QLD, Australia.; Faculty of Medicine, University of Queensland, St Lucia, QLD, Australia., Pinto N; Department of Vascular Surgery, The Royal Brisbane and Women's Hospital, Herston, QLD, Australia.; Herston Biofabrication Institute, Royal Brisbane and Women's Hospital, Herston, QLD, Australia., Peden S; Department of Vascular Surgery, The Royal Brisbane and Women's Hospital, Herston, QLD, Australia., Cohen T; Department of Vascular Surgery, The Princess Alexandra Hospital, Woolloongabba, QLD, Australia., Vallely MP; Department of Cardiovascular Surgery, Mount Sinai Morningside/Icahn School of Medicine, New York, NY, United States., McGiffin D; Department of Cardiothoracic Surgery, The Alfred Hospital, Melbourne, VIC, Australia.; Faculty of Medicine, Monash University, Melbourne, Australia., Naidoo R; Department of Cardiothoracic Surgery, The Prince Charles Hospital, Chermside, QLD, Australia., Jenkins J; Department of Vascular Surgery, The Royal Brisbane and Women's Hospital, Herston, QLD, Australia.; Herston Biofabrication Institute, Royal Brisbane and Women's Hospital, Herston, QLD, Australia., Suen JY; Critical Care Research Group, The Prince Charles Hospital, Chermside, QLD, Australia.; Faculty of Medicine, University of Queensland, St Lucia, QLD, Australia., Fraser JF; Critical Care Research Group, The Prince Charles Hospital, Chermside, QLD, Australia.; Faculty of Medicine, University of Queensland, St Lucia, QLD, Australia.
Jazyk:	angličtina
Zdroj:	Frontiers in surgery [Front Surg] 2022 Aug 26; Vol. 9, pp. 956177. Date of Electronic Publication: 2022 Aug 26 (Print Publication: 2022).
DOI:	10.3389/fsurg.2022.956177
Abstrakt:	During bypass surgery for peripheral arterial occlusive disease and ischaemic heart disease, autologous graft conduit including great saphenous veins and radial arteries are frequently stored in solution. Endothelial damage adversely affects the performance and patency of autologous bypass grafts, and intraoperative graft storage solutions have been shown to influence this process. The distribution of storage solutions currently used amongst Cardiothoracic and Vascular Surgeons from Australia and New Zealand is not well defined in the literature. The aim of this study was to determine current practices regarding autologous graft storage and handling amongst this cohort of surgeons, and discuss their potential relevance in the context of early graft failure. From this survey, the most frequently used storage solutions were heparinized saline for great saphenous veins, and pH-buffered solutions for radial arteries. Duration of storage was 30-45 min for almost half of respondents, although responses to this question were limited. Further research is required to investigate whether ischaemic endothelial injury generates a prothrombotic state, whether different storage media can alter this state, and whether this is directly associated with clinical outcomes of interest such as early graft failure. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (© 2022 Haymet, Pinto, Peden, Cohen, Vallely, McGiffin, Naidoo, Jenkins, Suen and Fraser.)
Databáze:	MEDLINE
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