Advances in the treatment of pediatric solid tumors: A 50-year perspective.

Autor: LaQuaglia MP; Pediatric Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Gerstle JT; Pediatric Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Jazyk: angličtina
Zdroj: Journal of surgical oncology [J Surg Oncol] 2022 Oct; Vol. 126 (5), pp. 933-942.
DOI: 10.1002/jso.27038
Abstrakt: In the United States, more than 10 000 cancers occur annually in children aged 0-14 years, and more than 5000 in adolescents aged 15-19. In the last 50 years, significant advances have been made in imaging, molecular pathology, stage and risk assessment, surgical approach, multidisciplinary treatment, and survival for pediatric solid tumors (particularly neuroblastoma, Wilms tumor, rhabdomyosarcoma, and hepatoblastoma). Moreover, the molecular driver for fibrolamellar hepatocellular carcinoma, which occurs in adolescence and young adulthood, has been identified.
(© 2022 Wiley Periodicals LLC.)
Databáze: MEDLINE
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