A Rare Presentation of Sarcomatoid Carcinoma of Duodenum: A Case Report.

Autor: Reyes JV; Icahn School of Medicine at Mount Sinai Hospital (Elmhurst Hospital Center), New York, NY, USA., Seen T; Icahn School of Medicine at Mount Sinai Hospital (Elmhurst Hospital Center), New York, NY, USA., Singh B; Icahn School of Medicine at Mount Sinai Hospital (Elmhurst Hospital Center), New York, NY, USA., Walfish A; Icahn School of Medicine at Mount Sinai Hospital (Elmhurst Hospital Center), New York, NY, USA.
Jazyk: angličtina
Zdroj: Journal of investigative medicine high impact case reports [J Investig Med High Impact Case Rep] 2022 Jan-Dec; Vol. 10, pp. 23247096221121392.
DOI: 10.1177/23247096221121392
Abstrakt: Sarcomatoid tumors are very rare biphasic tumors characterized by a mixture of malignant epithelial and mesenchymal cells that have been usually identified in the lungs with other documented cases in skin, bone, thyroid gland, salivary glands, breast, and genitourinary and gastrointestinal systems. They have an incidence estimated to be 0.5 to 0.8 per 100 000 per year. Three classic features include the presence of a genuine sarcomatous component, no transitional zone between carcinomatous and sarcomatous components, and immunohistochemistry of the sarcomatous component that is positive for mesenchymal markers and negative for epithelial markers. Sarcomatoid carcinoma of the gastrointestinal tract is rare but more commonly found within the stomach, gallbladder, and esophagus. Small bowel involvement is very rare.
Databáze: MEDLINE