CONVENTIONAL INTERNAL LIMITING MEMBRANE PEELING VERSUS INVERTED FLAP FOR SMALL-TO-MEDIUM IDIOPATHIC MACULAR HOLE: A Randomized Trial.

Autor:	Ventre L; Department of Surgical Sciences, Eye Clinic Section, University of Turin, Turin, Italy., Fallico M; Department of Ophthalmology, University of Catania, Catania, Italy., Longo A; Department of Ophthalmology, University of Catania, Catania, Italy., Parisi G; Department of Surgical Sciences, Eye Clinic Section, University of Turin, Turin, Italy., Russo A; Department of Ophthalmology, University of Catania, Catania, Italy., Bonfiglio V; Department of Experimental Biomedicine and Clinical Neuroscience, Ophthalmology Section, University of Palermo, Palermo, Italy; and., Marolo P; Department of Surgical Sciences, Eye Clinic Section, University of Turin, Turin, Italy., Caselgrandi P; Department of Surgical Sciences, Eye Clinic Section, University of Turin, Turin, Italy., Avitabile T; Department of Ophthalmology, University of Catania, Catania, Italy., Borrelli E; Vita-Salute San Raffaele University, Milan, Italy., Reibaldi M; Department of Surgical Sciences, Eye Clinic Section, University of Turin, Turin, Italy.
Jazyk:	angličtina
Zdroj:	Retina (Philadelphia, Pa.) [Retina] 2022 Dec 01; Vol. 42 (12), pp. 2251-2257. Date of Electronic Publication: 2022 Sep 06.
DOI:	10.1097/IAE.0000000000003622
Abstrakt:	Purpose: To compare conventional internal limiting membrane (ILM) peeling versus inverted flap technique in small-to-medium idiopathic macular hole. Methods: Eyes with ≤400 μ m idiopathic macular holes were randomized into the conventional ILM peeling group (25 eyes) and inverted flap group (25 eyes). A 12-month follow-up was considered. Macular sensitivity (MS) change detected with MP-1 microperimetry was the primary outcome. Secondary outcomes included best-corrected visual acuity change, closure rate, anatomical findings on optical coherence tomography such as U-shape foveal contour, restoration of external limiting membrane, and ellipsoid zone. Results: In both groups, MS improved throughout the follow-up. Final MS was greater in the conventional ILM peeling group compared with the inverted flap group, being 16.6 ± 2.3 dB versus 14.9 ± 2.9 dB, respectively ( P = 0.026). In both groups best-corrected visual acuity improved throughout the follow-up, with a final best-corrected visual acuity of 0.19 ± 0.14 logMar (20/31 Snellen) in the conventional ILM group and 0.22 ± 0.11 logMar (20/33 Snellen) in the inverted flap group ( P = 0.398). Anatomical hole closure was achieved in all cases. No difference in optical coherence tomography findings was shown between the two groups. Conclusion: A better final MS was found in eyes undergoing conventional ILM peeling. Inverted flap technique has disadvantages compared with conventional peeling for the treatment of small-to-medium idiopathic macular holes. (Copyright © 2022 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the Opthalmic Communications Society, Inc.)
Databáze:	MEDLINE
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