| Autor: |
Ng ZHC; Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore., Ho SJ; Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore., Caleb T; Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore., Yaow CYL; Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore., Teoh SE; Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore., Tham LP; Children's Emergency, KK Women's and Children's Hospital, Singapore 229899, Singapore., Ong MEH; Department of Emergency Medicine, Singapore General Hospital, Singapore 169608, Singapore.; Pre-Hospital and Emergency Research Centre, Health Services and Systems Research, Duke-NUS Medical School, Singapore 169857, Singapore., Chong SL; Children's Emergency, KK Women's and Children's Hospital, Singapore 229899, Singapore.; Duke-NUS Medical School, Singapore 169857, Singapore., Ho AFW; Department of Emergency Medicine, Singapore General Hospital, Singapore 169608, Singapore.; Pre-Hospital and Emergency Research Centre, Health Services and Systems Research, Duke-NUS Medical School, Singapore 169857, Singapore. |
| Abstrakt: |
Long-term outcomes after non-traumatic pediatric out-of-hospital cardiac arrest (OHCA) are not well understood. This systematic review aimed to summarize long-term outcomes (1 year and beyond), including overall survival, survival with favorable neurological outcomes, and health-related quality of life (HRQoL) outcomes) amongst pediatric OHCA patients who survived to discharge. Embase, Medline, and The Cochrane Library were searched from inception to October 6, 2021. Studies were included if they reported outcomes at 1 year or beyond after pediatric OHCA. Data abstraction and quality assessment was conducted by three authors independently. Qualitative outcomes were reported systematically. Seven studies were included, and amongst patients that survived to hospital discharge or to 30 days, longer-term survival was at least 95% at 24 months of follow up. A highly variable proportion (range 10-71%) of patients had favorable neurological outcomes at 24 months of follow up. With regard to health-related quality of life outcomes, at a time point distal to 1 year, at least 60% of pediatric non-traumatic OHCA patients were reported to have good outcomes. Our study found that at least 95% of pediatric OHCA patients, who survived to discharge, survived to a time point distal to 1 year. There is a general paucity of data surrounding the pediatric OHCA population. |
