Do Probiotics Prevent Clostridium difficile-Associated Diarrhea?
| Autor: | Al Sharaby A; Internal Medicine, Michigan State University, San Francisco, USA., Abugoukh TM; Medicine, Shendi University, Cedar Rapids, USA., Ahmed W; Pediatric Infectious Diseases, Sunydown State Medical Center, New York City, USA., Ahmed S; Internal Medicine, Michigan State University, Saskatoon, CAN., Elshaikh AO; Internal Medicine/Family Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2022 Aug 02; Vol. 14 (8), pp. e27624. Date of Electronic Publication: 2022 Aug 02 (Print Publication: 2022). |
| DOI: | 10.7759/cureus.27624 |
| Abstrakt: | Clostridium difficile is a bacterium that affects the gastrointestinal tract and is the leading cause of antibiotic-associated diarrhea. A wide range of probiotics has been studied and used to prevent or treat Clostridium difficile-associated diarrhea (CDAD). Probiotics are microorganisms with unique characteristics that suppress dangerous gut bacteria through several mechanisms. The main objective of this study is to evaluate the efficacy and safety of probiotics in the prevention of CDAD. In this literature review, we searched PubMed and Google Scholar databases to gather related articles depending on predetermined eligibility criteria and found 13 papers of different study designs. We found that probiotics have promising effects in preventing CDAD. Additionally, they were safe and well-tolerated. Further randomized clinical trials with larger sample sizes and various patient groups are needed to better understand the advantages of probiotics and recommend the best dose and duration of probiotic treatment. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2022, Al Sharaby et al.) |
| Databáze: | MEDLINE |
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