The Catalytic Synthesis of N -Aryl Indoles Featuring an Alternative Disconnection. Hydroaminoalkylation for a Telescoped Reaction Sequence.
Autor: | Zheng CHM; Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, British Columbia Canada V6T 1Z1., Balatsky DA; Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, British Columbia Canada V6T 1Z1., DiPucchio RC; Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, British Columbia Canada V6T 1Z1., Schafer LL; Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, British Columbia Canada V6T 1Z1. |
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Jazyk: | angličtina |
Zdroj: | Organic letters [Org Lett] 2022 Sep 16; Vol. 24 (36), pp. 6571-6575. Date of Electronic Publication: 2022 Sep 07. |
DOI: | 10.1021/acs.orglett.2c02510 |
Abstrakt: | A tricatalytic telescoped synthesis toward C3-methyl- N -aryl indoline and indole products is reported. An in situ generated tantalum(V) ureate catalyst is used for the hydroaminoalkylation of o -chlorostyrene with N -methylaniline to first make a C |
Databáze: | MEDLINE |
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