Value of Immunohistochemistry to Differentiate Digital Papillary Adenocarcinoma From Acral Hidradenoma With Papillary Structures.
| Autor: | Xavier-Júnior JCC; School of Medicine, Centro Universitário Unisalesiano Auxilium, Araçatuba, SP, Brazil.; Pathology Institute of Araçatuba, Araçatuba, SP, Brazil.; School of Medicine, São Paulo State University-UNESP, Botucatu, SP, Brazil., Camilo-Júnior DJ; Pathology Institute of Araçatuba, Araçatuba, SP, Brazil., Carneiro Dias AL; Private Clinic, Araçatuba, SP, Brazil; and., Marques Ferreira PP; Private Clinic, Araçatuba, SP, Brazil; and., Abdalla Filho AR; Private Clinic, Araçatuba, SP, Brazil; and., Brenn T; Department of Pathology and Laboratory Medicine, Arnie Charbonneau Cancer Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada. |
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| Jazyk: | angličtina |
| Zdroj: | The American Journal of dermatopathology [Am J Dermatopathol] 2022 Nov 01; Vol. 44 (11), pp. 843-845. Date of Electronic Publication: 2022 Sep 01. |
| DOI: | 10.1097/DAD.0000000000002291 |
| Abstrakt: | Abstract: Digital papillary adenocarcinoma is a malignant adnexal tumor with a predilection for acral sites. Hidradenoma is a benign solid and cystic sweat gland neoplasm with focal ductal and glandular differentiation and good outcomes. Hidradenomas can occur at acral sites and show papillary structures; for this reason, they are included in the differential diagnosis of digital papillary adenocarcinoma, and immunohistochemistry is a valuable tool in this scenario. We described a case of a 43-year-old man with an epithelial tumor showing papillary structures in the intermediate phalanx of the fourth finger. There was diffuse positivity for p63 and negativity for S100 protein, suggesting that this tumor was an acral hidradenoma with papillary structures. Competing Interests: The authors declare no conflicts of interest. (Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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