Initial Assessment and Monitoring of Patients with Chronic Hypoparathyroidism: A Systematic Current Practice Survey.

Autor: Van Uum S; Department of Medicine, Western University, London, ON, Canada., Shrayyef M; Dept of Medicine, University of Toronto, Toronto, ON, Canada., M'Hiri I; Bone Research and Education Centre, Oakville, ON, Canada., Dandurand K; Division of Endocrinology and Metabolism, McMaster University, Hamilton, ON, Canada., Ali DS; Division of Endocrinology and Metabolism, McMaster University, Hamilton, ON, Canada., Bilezikian JP; Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA., Collins MT; National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA., Mannstadt M; Endocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Rubin MR; Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA., Siggelkow H; Clinic of Gastroenterology, Gastrointestinal Oncology and Endocrinology, University Medical Center Goettingen, Goettingen, Germany.; MVZ Endokrinologikum Goettingen, Goettingen, Germany., Tabacco G; Unit of Endocrinology and Diabetes, Campus Bio-Medico University of Rome, Rome, Italy., Tay YD; Department of Medicine, Sengkang General Hospital, Singhealth and Duke-NUS Medical School, Singapore, Singapore., Vokes T; University of Chicago, Chicago, IL, USA., Winer KK; Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA., Yao L; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, Canada., Guyatt G; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, Canada., Rejnmark L; Dept of Endocrinology and Internal Medicine, Aarhus University hospital, Aarhus, Denmark., Khan AA; Division of Endocrinology and Metabolism, McMaster University, Hamilton, ON, Canada.
Jazyk: angličtina
Zdroj: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research [J Bone Miner Res] 2022 Dec; Vol. 37 (12), pp. 2630-2641. Date of Electronic Publication: 2022 Nov 14.
DOI: 10.1002/jbmr.4698
Abstrakt: Chronic hypoparathyroidism (HypoPT) is associated with significant morbidity and impaired quality of life (QoL). The goals of management for chronic HypoPT include improvement in QoL and the prevention of both hypo- and hypercalcemia symptoms and long-term complications. Several groups have provided consensus statements and guidelines on the management of HypoPT; however, due to limited evidence, these recommendations have largely been based on literature reviews, expert opinion, and consensus statements. The objective of this study was to use a systematic approach to describe current practice for the initial assessment and follow-up of patients with chronic HypoPT. We developed a survey asking experts in the field to select the responses that best reflect their current practice. The survey found no differences in responses between nonsurgical and postsurgical patient assessment. For new patients, respondents usually performed an assessment of serum lab profile (calcium [either albumin-adjusted or ionized], magnesium, creatinine, phosphate, 25-hydroxyvitamin D), 24-hour urine (creatinine, calcium), and a renal ultrasound to evaluate for the presence of nephrocalcinosis or nephrolithiasis. For follow-up patients, most respondents perform blood tests and urine tests every 6 months or less frequently. The reported clinical practice patterns for monitoring for complications of chronic HypoPT vary considerably among respondents. Based on the responses in this systematic expert practice survey, we provide practice suggestions for initial assessment and follow-up of patients with chronic HypoPT. In addition, we highlight areas with significant variation in practice and identify important areas for future research. © 2022 The Authors. Journal of Bone and Mineral Research published by Wiley Periodicals LLC on behalf of American Society for Bone and Mineral Research (ASBMR).
(© 2022 The Authors. Journal of Bone and Mineral Research published by Wiley Periodicals LLC on behalf of American Society for Bone and Mineral Research (ASBMR).)
Databáze: MEDLINE
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