Co-occurring depression and obsessive-compulsive disorder: A dimensional network approach.

Autor: Hellberg SN; Department of Psychology & Neuroscience, University of North Carolina, Chapel Hill, USA. Electronic address: shellberg@unc.edu., Abramowitz JS; Department of Psychology & Neuroscience, University of North Carolina, Chapel Hill, USA., Ojalehto HJ; Department of Psychology & Neuroscience, University of North Carolina, Chapel Hill, USA., Butcher MW; Department of Psychology & Neuroscience, University of North Carolina, Chapel Hill, USA., Buchholz JL; Department of Psychology & Neuroscience, University of North Carolina, Chapel Hill, USA., Riemann BC; Rogers Behavioral Health System, Oconomowoc, WI, USA.
Jazyk: angličtina
Zdroj: Journal of affective disorders [J Affect Disord] 2022 Nov 15; Vol. 317, pp. 417-426. Date of Electronic Publication: 2022 Aug 30.
DOI: 10.1016/j.jad.2022.08.101
Abstrakt: Background: Depressive and obsessive-compulsive (OCD) symptoms often co-occur and a number of possible explanations for this co-occurrence have been explored, including shared biological and psychosocial risk factors. Network approaches have offered a novel hypothesis for the link between depression and OCD: functional inter-relationships across the symptoms of these conditions. The few network studies in this area have relied largely on item, rather than process-level constructs, and have not examined relationships dimensionally.
Methods: Network analytic methods were applied to data from 463 treatment-seeking adults with OCD. Patients completed self-report measures of OCD and depression. Factor analysis was used to derive processes (i.e., nodes) to include in the network. Networks were computed, and centrality, bridge, and stability statistics examined.
Results: Networks showed positive relations among specific OCD and depressive symptoms. Obsessions (particularly repugnant thoughts), negative affectivity, and cognitive-somatic changes (e.g., difficulty concentrating) were central to the network. Unique relations were observed between symmetry OCD symptoms and cognitive-somatic changes. No direct link between harm-related OCD symptoms and depression was observed.
Conclusions: Our results bring together prior findings, suggesting that both negative affective and psychomotor changes are important to consider in examining the relationship between OCD and depression. Increased consideration of heterogeneity in the content of OCD symptoms is key to improving clinical conceptualizations, particularly when considering the co-occurrence of OCD with other disorders.
Competing Interests: Conflict of interest None to disclose.
(Copyright © 2022 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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