Arterial Stiffness and Endothelial Function are Comparable in Young Healthy Vegetarians and Omnivores.

Autor: Gonzalez MR; Department of Kinesiology and Applied Physiology, University of Delaware, Newark, DE 19713, USA., Zuelch ML; Department of Behavioral Health and Nutrition, University of Delaware, Newark, DE 19713, USA., Smiljanec K; Department of Kinesiology and Applied Physiology, University of Delaware, Newark, DE 19713, USA., Mbakwe AU; Department of Kinesiology and Applied Physiology, University of Delaware, Newark, DE 19713, USA., Axler MR; Department of Kinesiology and Applied Physiology, University of Delaware, Newark, DE 19713, USA., Witman MA; Department of Kinesiology and Applied Physiology, University of Delaware, Newark, DE 19713, USA., Lennon SL; Department of Kinesiology and Applied Physiology, University of Delaware, Newark, DE 19713, USA. Electronic address: slennon@udel.edu.
Jazyk: angličtina
Zdroj: Nutrition research (New York, N.Y.) [Nutr Res] 2022 Sep; Vol. 105, pp. 163-172. Date of Electronic Publication: 2022 Jul 29.
DOI: 10.1016/j.nutres.2022.07.002
Abstrakt: Vegetarians (VEG) are reported to have lower body weight, blood pressure (BP), and cardiovascular disease (CVD) risk compared with omnivores (OMN), yet the mechanisms remain unclear. A vegetarian diet may protect the vascular endothelium, reducing the risk of atherosclerosis and CVD. This cross-sectional study compared vascular function between OMN and VEG. We hypothesized that VEG would have greater vascular function compared with OMN. Fifty-eight normotensive young healthy adults participated (40 women [W]/18 men [M]; 28 OMN [15W/13M] and 30 VEG [25W/5M]; 26 ± 7 years; BP: 112 ± 11/67 ± 8 mm Hg). Arterial stiffness, assessed by carotid-to-femoral pulse wave velocity (OMN: 5.6 ± 0.8 m/s, VEG: 5.3 ± 0.8 m/s; P = .17) and wave reflection assessed by aortic augmentation index (OMN: 6.9 ± 12.3%, VEG: 8.8 ± 13.5%; P = .57) were not different between groups. However, central pulse pressure (OMN: 32 ± 5; VEG: 29 ± 5 mm Hg; P = .048) and forward wave reflection were greater in omnivores (OMN: 26 ± 3; VEG: 24 ± 3 mm Hg; P = .048). Endothelial-dependent dilation measured by brachial artery flow-mediated dilation was not different between groups (OMN: 6.0 ± 2.9%, VEG: 6.9 ± 3.3%; P = .29). Percent change in femoral blood flow from baseline during passive leg movement, another assessment of nitric oxide-mediated endothelial dilation, was similar between groups (OMN: 203 ± 88 mL/min, VEG: 253 ± 192 mL/min; P = .50). These data suggest that in healthy young adults, normotensive VEG do not have significantly improved vascular function compared with OMN; however, they have a lower central pulse pressure and forward wave amplitude which may lower the risk of future CVD.
Competing Interests: Declaration of Competing Interest The authors declare that there are no conflicts of interests.
(Copyright © 2022. Published by Elsevier Inc.)
Databáze: MEDLINE
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