Low fat diet versus low carbohydrate diet for management of non-alcohol fatty liver disease: A systematic review.

Autor:	Varkaneh HK; Student Research Committee, Department of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Poursoleiman F; Student Research Committee, Department of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Al Masri MK; College of Medicine, Alfaisal University, Riyadh, Saudi Arabia., Alras KA; College of Medicine, Alfaisal University, Riyadh, Saudi Arabia., Shayah Y; College of Medicine, Alfaisal University, Riyadh, Saudi Arabia., Masmoum MD; College of Medicine, Alfaisal University, Riyadh, Saudi Arabia., Alangari FA; College of Medicine, Alfaisal University, Riyadh, Saudi Arabia., Alras AA; College of Kinesiology, University of Saskatchewan, Saskatoon, SK, Canada., Rinaldi G; St. George's Hospital, London, United Kingdom., Day AS; Department of Paediatrics, University of Otago, Dunedin, New Zealand., Hekmatdoost A; Student Research Committee, Department of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Abu-Zaid A; College of Medicine, Alfaisal University, Riyadh, Saudi Arabia.; Department Pharmacology, College of Graduate Health Sciences, The University of Tennessee Health Science Center, Memphis, TN, United States., Kutbi E; Department of Biorepository, Biomedical Research Administration, King Fahad Medical City, Riyadh, Saudi Arabia.
Jazyk:	angličtina
Zdroj:	Frontiers in nutrition [Front Nutr] 2022 Aug 16; Vol. 9, pp. 987921. Date of Electronic Publication: 2022 Aug 16 (Print Publication: 2022).
DOI:	10.3389/fnut.2022.987921
Abstrakt:	Although there is a consensus on beneficial effects of a low calorie diet in management of non-alcoholic fatty liver disease, the optimal composition of diet has not yet been elucidated. The aim of this review is to summarize the results of current randomized controlled trials evaluating the effects of low fat diet (LFD) vs. low carbohydrate diet (LCD) on NAFLD. This is a systematic review of all the available data reported in published clinical trials up to February 2022. The methodological quality of eligible studies was assessed, and data were presented aiming specific standard measurements. A total of 15 clinical trial studies were included in this systematic review. There is an overall lack of consensus on which dietary intervention is the most beneficial for NAFLD patients. There is also an overall lack of consensus on the definition of the different restrictive diets and the percentage of macronutrient restriction recommended. It seems that low calorie diets, regardless of their fat and carbohydrate composition, are efficient for liver enzyme reduction. Both LCD and LFD have similar effects on liver enzymes change; however, this improvement tends to be more marked in LFD. All calorie restrictive dietary interventions are beneficial for reducing weight, liver fat content and liver enzymes in individuals with NAFLD. Low fat diets seem to be markedly successful in reducing transaminase levels. Further research is needed to explore diet intensity, duration and long-term outcome. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2022 Varkaneh, Poursoleiman, Al Masri, Alras, Shayah, Masmoum, Alangari, Alras, Rinaldi, Day, Hekmatdoost, Abu-Zaid and Kutbi.)
Databáze:	MEDLINE
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