Interventions for Enuresis in Children and Adolescents: An Overview of Systematic Reviews.

Autor:	Correia Moretti E; Department of Anatomy, Federal University of Pernambuco, Child and Adolescent Health, Federal University of Pernambuco - Recife (PE), Brazil.; Institute of Biological and Health Sciences, Federal University of Alagoas (UFAL), Maceió, Alagoas, Brazil., da Silva IB; Department of Morphology, Federal University of Paraiba - João Pessoa (PB), Brazil., Boaviagem A; Department of Physiotherapy, Federal University of Pernambuco - Recife (PE), Brazil., de Lima AMJ; Department of Animal Morphology and Physiology, Federal Rural University of Pernambuco - Recife (PE), Brazil., Lemos A; Department of Physical Therapy, Federal University of Pernambuco, Recife (PE), Brazil.
Jazyk:	angličtina
Zdroj:	Current pediatric reviews [Curr Pediatr Rev] 2024; Vol. 20 (1), pp. 76-88.
DOI:	10.2174/1573396318666220827103731
Abstrakt:	Background: Enuresis is an involuntary and intermittent loss of urine during sleep, and its treatment can be done by pharmacological and non-pharmacological strategies. Objective: To conduct an overview to carry out a survey of the systematic reviews about treatment options for children/adolescents with enuresis. Methods: Databases used were Cochrane Library, PROSPERO, MEDLINE/PubMed, EMBASE, LILACS/BVS, PEDro, SciELO and Google Scholar. Any type of intervention for the treatment of enuresis in children/adolescents was selected by two independent researchers. Data extraction was done by two independent researchers. The risk of bias was assessed using Risk of Bias in Systematic Reviews (ROBIS) and A MeaSurement Tool to Assess Systematic Reviews (AMSTAR-2). Results: Seven systematic reviews were included. According to ROBIS, three reviews had a low risk of bias, while the others had a high risk of bias. Based on AMSTAR-2, four systematic reviews were of moderate quality, two were low quality, and one was critically low quality. Conclusion: There is moderate confidence that the use of desmopressin plus an anticholinergic agent increases the chance of complete response compared to desmopressin alone. Neurostimulation may increase the risk of responses ≥50% and ≥90% compared to the control group. Likewise, it appears that electrical stimulation is superior to placebo about the chance of response ≥50%. In addition, there is clinical relevance in reducing enuresis episodes per week when neurostimulation is used compared to control groups. (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.)
Databáze:	MEDLINE
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