Retrospective case series: Necrotising fasciitis in 23 dogs.

Autor: Quilling LL; William R. Pritchard Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis, California, USA., Outerbridge CA; Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, California, USA., White SD; Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, California, USA., Affolter VK; Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis, California, USA.
Jazyk: angličtina
Zdroj: Veterinary dermatology [Vet Dermatol] 2022 Dec; Vol. 33 (6), pp. 534-544. Date of Electronic Publication: 2022 Aug 31.
DOI: 10.1111/vde.13113
Abstrakt: Background: Necrotising fasciitis (NF) is a rare, rapidly progressive subcutaneous bacterial infection. Few studies have characterised NF in dogs.
Hypothesis/objectives: To retrospectively describe clinical and laboratory findings, with treatments and outcomes, in dogs with NF.
Animals: Twenty-three client-owned dogs treated at a veterinary teaching hospital between 1998 and 2021.
Materials and Methods: Medical records and laboratory data from 23 dogs diagnosed with NF were reviewed.
Results: Male dogs were significantly over-represented (p = 0.003). The most common presenting complaint was sudden lameness. Infection occurred in one or two limbs in 19 of 23 dogs, with right hindlimbs most often affected (13 of 23). Pitting oedema was evident in 14 of 23 dogs. Antibiotic and nonsteroidal anti-inflammatory drugs were administered before presentation in nine and 13 of 23 dogs, respectively. Common clinicopathological abnormalities included hypoalbuminemia, hyponatremia, elevated liver enzymes, elevated creatine kinase, increased bands and lymphopenia. Streptococcus canis was isolated from 18 of 23 dogs. Histopathological features included acute necrosis and severe neutrophilic inflammation. Fifteen dogs were euthanised or died, while surgical intervention led to survival in eight of 23 dogs.
Conclusions and Clinical Relevance: Dogs presenting for acute swelling of a limb with oedema should have the diagnosis of NF considered and early surgical intervention might increase survival.
(© 2022 ESVD and ACVD.)
Databáze: MEDLINE
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