Acquired Amegakaryocytic Thrombocytopenia Associated With Autoimmune Hemolytic Anemia.

Autor: Ikeda N; Internal Medicine, Kaneda Hospital, Okayama, JPN., Hisano Y; Internal Medicine, Kaneda Hospital, Okayama, JPN., Kamao T; Internal Medicine, Kaneda Hospital, Okayama, JPN., Uno M; Internal Medicine, Kaneda Hospital, Okayama, JPN., Mizushima T; Internal Medicine, Kaneda Hospital, Okayama, JPN.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2022 Jul 26; Vol. 14 (7), pp. e27315. Date of Electronic Publication: 2022 Jul 26 (Print Publication: 2022).
DOI: 10.7759/cureus.27315
Abstrakt: Acquired amegakaryocytic thrombocytopenia (AATP) is a thrombocytopenic disorder characterized by a decrease in megakaryocytes in the bone marrow. AATP is effectively treated with immunosuppressive therapy. We report a case of a 68-years-old male referred to us due to purpuric lesions on the extremities and was noted to be thrombocytopenic. Bone marrow biopsy showed AATP with autoimmune hemolytic anemia (AIHA). Only two cases of AATP associated with AIHA have been reported. AATP should be differentiated carefully from other causes of peripheral destruction of platelets, such as immune thrombocytopenia (ITP).
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2022, Ikeda et al.)
Databáze: MEDLINE