Diagnosis and treatment of acute lymphoblastic leukemia in Latin America.

Autor: Colunga-Pedraza PR; Universidad Autónoma de Nuevo León, Facultad de Medicina, Servicio de Hematología, Hospital Universitario 'Dr. José E. González', Monterrey, Mexico., Colunga-Pedraza JE; Universidad Autónoma de Nuevo León, Facultad de Medicina, Servicio de Hematología, Hospital Universitario 'Dr. José E. González', Monterrey, Mexico., Peña-Lozano SP; Universidad Autónoma de Nuevo León, Facultad de Medicina, Servicio de Hematología, Hospital Universitario 'Dr. José E. González', Monterrey, Mexico., Gómez-De León A; Universidad Autónoma de Nuevo León, Facultad de Medicina, Servicio de Hematología, Hospital Universitario 'Dr. José E. González', Monterrey, Mexico., Ruiz-Delgado GJ; Centro de Hematología y Medicina Interna, Clínica RUIZ, Puebla, Mexico.; Universidad Popular Autónoma del Estado de Puebla, Puebla, México., Ribeiro RC; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Jazyk: angličtina
Zdroj: Hematology (Amsterdam, Netherlands) [Hematology] 2022 Dec; Vol. 27 (1), pp. 971-976.
DOI: 10.1080/16078454.2022.2117119
Abstrakt: Objective: to discuss the status and challenges associated with the management of acute lymphoblastic leukemia (ALL) in Latin America.
Methods: This review summarizes various insights gained from information regarding diagnostic approaches and treatment strategies in adult patients with ALL in Latin American Countries.
Results: Information regarding ALL in Latin America is scarce; however, many efforts have been made to overcomes these barriers. Nevertheless, major obstacles to successful treatment in Latin America and LMIC remain poor adherence, abandonment of treatment, and lack of supportive therapy and new therapeutic agents.
Conclusion: Further improvements in survival should be pursued by developing more Latin American registries, forming cooperative groups, developing educational models to facilitate earlier diagnosis and prevention of complications, better support therapy and management of infections, and adapting treatment strategies.
Databáze: MEDLINE
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