Skeletal scintigraphy as an important complement for detecting bone metastasis from nasopharyngeal carcinoma.

Autor:	Yen WJ; Department of Nuclear Medicine, Kaohsiung Medical University Hospital, Kaohsiung., Liu CT; Department of Nuclear Medicine, Kaohsiung Medical University Hospital, Kaohsiung., Chi YM; Department of Nuclear Medicine, Kaohsiung Medical University Hospital, Kaohsiung., Chang CC; Department of Nuclear Medicine, Kaohsiung Medical University Hospital, Kaohsiung.; Department of Electrical Engineering, I-Shou University, Kaohsiung.; School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung.; Department of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung.; Neuroscience Research Center, Kaohsiung Medical University, Kaohsiung.
Jazyk:	angličtina
Zdroj:	The Journal of international medical research [J Int Med Res] 2022 Aug; Vol. 50 (8), pp. 3000605221116765.
DOI:	10.1177/03000605221116765
Abstrakt:	Bone metastasis occurs frequently in patients with nasopharyngeal carcinoma (NPC). Although fluorine-18 fluorodeoxyglucose positron emission tomography with computed tomography (PET/CT) has been proven to be more sensitive at detecting bone metastases than Technetium-99m methylene diphosphonate skeletal scintigraphy in pretreatment patients with NPC in most clinical settings, there have been metastatic lesions that were positive on skeletal scintigraphy but negative on PET/CT scans. Herein, we report the case of a patient with stage IV NPC that manifested as multiple metabolically abnormal lesions on pretreatment skeletal scintigraphy and were considered malignant although they were negative on PET/CT examination. Follow-up evaluations with both skeletal scintigraphy and PET/CT scans as post-therapeutic imaging are also presented.
Databáze:	MEDLINE
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