A Worldwide Survey of Activities and Practices in Clinical Islet of Langerhans Transplantation.

Autor:	Berney T; Division of Transplantation, Department of Surgery, University of Geneva Hospitals, Geneva, Switzerland., Andres A; Division of Transplantation, Department of Surgery, University of Geneva Hospitals, Geneva, Switzerland., Bellin MD; Departments of Pediatrics and Surgery, University of Minnesota Medical Center, Minneapolis, MN, United States., de Koning EJP; Department of Medicine, Leiden University Medical Center, Leiden, Netherlands., Johnson PRV; Nuffield Department of Surgical Sciences, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom., Kay TWH; Department of Medicine, St. Vincent's Hospital, St. Vincent's Institute of Medical Research, University of Melbourne, Melbourne, VIC, Australia., Lundgren T; Department of Transplantation Surgery, Karolinska University Hospital, Stockholm, Sweden., Rickels MR; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Institute for Diabetes, Obesity and Metabolism, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States., Scholz H; Department of Transplant Medicine, Institute for Surgical Research, Oslo University Hospital, Oslo, Norway., Stock PG; Division of Transplantation, Department of Surgery, University of California at San Francisco, San Francisco, CA, United States., White S; Department of HPB and Transplant Surgery, The Freeman Hospital, Newcastle Upon Tyne, United Kingdom.
Jazyk:	angličtina
Zdroj:	Transplant international : official journal of the European Society for Organ Transplantation [Transpl Int] 2022 Aug 11; Vol. 35, pp. 10507. Date of Electronic Publication: 2022 Aug 11 (Print Publication: 2022).
DOI:	10.3389/ti.2022.10507
Abstrakt:	A global online survey was administered to 69 islet transplantation programs, covering 84 centers and 5 networks. The survey addressed questions on program organization and activity in the 2000-2020 period, including impact on activity of national health care coverage policies. We obtained full data from 55 institutions or networks worldwide and basic activity data from 6 centers. Additional data were obtained from alternative sources. A total of 94 institutions and 5 networks was identified as having performed islet allotransplantation. 4,365 islet allotransplants (2,608 in Europe, 1,475 in North America, 135 in Asia, 119 in Oceania, 28 in South America) were reported in 2,170 patients in the survey period. From 15 centers active at the start of the study period, the number of simultaneously active islet centers peaked at 54, to progressively decrease to 26 having performed islet allotransplants in 2020. Notably, only 16 centers/networks have done >100 islet allotransplants in the survey period. Types of transplants performed differed notably between North America and the rest of the world, in particular with respect to the near-absence of simultaneous islet-kidney transplantation. Absence of heath care coverage has significantly hampered transplant activity in the past years and the COVID-19 pandemic in 2020. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2022 Berney, Andres, Bellin, de Koning, Johnson, Kay, Lundgren, Rickels, Scholz, Stock, White and the International Islet Transplant Centers.)
Databáze:	MEDLINE
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