Research in child and adolescent anxiety and depression: treatment uncertainties prioritised by youth and professionals.

Autor:	Axelsdóttir B; Regional Centre for Child and Adolescent Mental Health, Eastern and Southern Norway, Oslo, 0484, Norway., Eidet LM; Regional Centre for Child and Adolescent Mental Health, Eastern and Southern Norway, Oslo, 0484, Norway., Thoner R; Regional Centre for Child and Adolescent Mental Health, Eastern and Southern Norway, Oslo, 0484, Norway., Biedilæ S; Regional Centre for Child and Adolescent Mental Health, Eastern and Southern Norway, Oslo, 0484, Norway., Borren I; Regional Centre for Child and Adolescent Mental Health, Eastern and Southern Norway, Oslo, 0484, Norway., Elvsåshagen M; Regional Centre for Child and Adolescent Mental Health, Eastern and Southern Norway, Oslo, 0484, Norway., Ludvigsen KH; Regional Centre for Child and Adolescent Mental Health, Eastern and Southern Norway, Oslo, 0484, Norway., Dahlgren A; Regional Centre for Child and Adolescent Mental Health, Eastern and Southern Norway, Oslo, 0484, Norway.
Jazyk:	angličtina
Zdroj:	F1000Research [F1000Res] 2021 Dec 01; Vol. 10, pp. 1221. Date of Electronic Publication: 2021 Dec 01 (Print Publication: 2021).
DOI:	10.12688/f1000research.74205.2
Abstrakt:	Background: A starting point for evaluating the effectiveness of treatments should be to identify evidence gaps. Furthermore, such evaluations should consider the perspectives of patients, clinicians and carers to ensure relevance and potentially influence future research initiatives. Methods: Our approach, inspired by the James Lind Alliance methods, involved three steps. First, we performed a document analysis by identifying interventions and outcomes in two recently published overviews of systematic reviews, which summarised the effects of interventions for anxiety and depression in children and adolescents. Second, we surveyed children and adolescents with personal experiences of depression or anxiety as well as clinicians, and asked them to suggest treatments and outcomes associated with uncertainty. Finally, we facilitated a consensus process where clinicians and youth mental health patient representatives were invited to prioritise research uncertainties in separate consensus processes. Results: The survey included 674 respondents who reported a total of 1267 uncertainties. Independent coding by four investigators revealed 134 suggestions for treatments of anxiety, 90 suggestions for treatments of depression, 84 for outcomes of interventions for anxiety and 71 suggestions for outcomes of interventions for depression. Two separate priority setting workshops with eight clinicians and ten youth resulted in four independent top ten priority lists. Conclusion: Top ten lists of treatments and outcome domains of anxiety and depression in children and adolescents was identified by youth and clinicians. The results may influence the research agenda, and ultimately benefit patients. Competing Interests: No competing interests were disclosed. (Copyright: © 2022 Axelsdóttir B et al.)
Databáze:	MEDLINE
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