Biosynthesis and extrinsic toxicity of copper oxide nanoparticles against cattle parasites: An eco-friendly approach.

Autor: Kamaraj C; Interdisciplinary Institute of Indian System of Medicine (IIISM), Directorate of Research and Virtual Education, SRM Institute of Science and Technology (SRMIST), Kattankulathur, 603203, Tamil Nadu, India. Electronic address: kamarajc@srmist.edu.in., Gandhi PR; Division of Nano-biotechnology, Department of Zoology, Auxilium College (Autonomous), Gandhi Nagar, 632 006, Vellore District, Tamil Nadu, India. Electronic address: raju87msc@gmail.com., Chandra Satish Kumar R; Interdisciplinary Institute of Indian System of Medicine (IIISM), Head - Drug Testing Laboratory (Indian Medicine), S.R.M. Institute of Science & Technology, Chengalpattu, 603 203, Tamil Nadu, India. Electronic address: ayursatish@gmail.com., Balasubramani G; Department of Research and Innovation, Saveetha School of Engineering (SSE), Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, 602105, Tamil Nadu, India. Electronic address: balabio62@gmail.com., Malafaia G; Laboratory of Toxicology Applied to the Environment, Goiano Federal Institute, Urutaí, GO, Brazil; Post-Graduation Program in Conservation of Cerrado Natural Resources, Goiano Federal Institute, Urutaí, GO, Brazil; Post-Graduation Program in Ecology, Conservation, and Biodiversity, Federal University of Uberlândia, Uberlândia, MG, Brazil; Post-Graduation Program in Biotechnology and Biodiversity, Federal University of Goiás, Goiânia, GO, Brazil. Electronic address: guilhermeifgoiano@gmail.com.
Jazyk: angličtina
Zdroj: Environmental research [Environ Res] 2022 Nov; Vol. 214 (Pt 4), pp. 114009. Date of Electronic Publication: 2022 Aug 24.
DOI: 10.1016/j.envres.2022.114009
Abstrakt: Plant extracts' ability to collect metals and decrease metal ions makes them a superior candidate for the biosynthesis of nanoparticles; hence, they are referred to as bio-nano factories since both living and dead dried biomass are employed to produce metallic nanoparticles. The antiparasitic activity of biosynthesized copper oxide nanoparticles (CuO NPs) was examined against cow tick larvae (Rhipicephalus microplus, Haemaphysalis bispinosa, and Hippobosca maculata). These parasitic larvae were treated with various concentrations of methanolic leaf extract of A. marmelos (MLE-AM) and biosynthesized CuO NPs for 24 h. CuO NPs were synthesized quickly using A. marmelos leaf extract, and nanoparticle synthesis was identified within 15 min. The results from characteristic XRD, FTIR, SEM, EDX, and TEM analyses confirmed the biosynthesis of CuO NPs. The presence of 26-Hydroxycholesterol was discovered as the predominant chemical present in the GC-MS analysis of MLE-AM. The maximum efficacy was observed in biosynthesized CuO NPs against R. microplus larvae, H. bispinosa adults, and Hip. maculata larvae (LC 50  = 4.30, 9.50, and 11.13 mg/L; and LC 90  = 8.30, 19.57, and 21.65 mg/L; and 6.219, 6.547, and 2.587). Overall, the bio-fabrication of CuO NPs has the potential to develop better and safer antiparasitic control techniques.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2022 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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