In vitro assessment of the acaricidal activity of a carvacrol shampoo on tick larvae.

Autor: Sousa AP; Laboratory of Plant Biochemistry, Federal University of Maranhão, São Luís, MA, Brazil., Castro GS; Laboratory of Plant Biochemistry, Federal University of Maranhão, São Luís, MA, Brazil., Tavares CP; Laboratory of Parasite Control, Federal University of Maranhão, São Luís, MA, Brazil., Vale TLD; Laboratory of Parasite Control, Federal University of Maranhão, São Luís, MA, Brazil., Costa-Junior LM; Laboratory of Parasite Control, Federal University of Maranhão, São Luís, MA, Brazil. Electronic address: livio.martins@ufma.br., Soares AS; Laboratory of Plant Biochemistry, Federal University of Maranhão, São Luís, MA, Brazil. Electronic address: alexandra.ufma@gmail.com.
Jazyk: angličtina
Zdroj: Experimental parasitology [Exp Parasitol] 2022 Nov; Vol. 242, pp. 108364. Date of Electronic Publication: 2022 Aug 24.
DOI: 10.1016/j.exppara.2022.108364
Abstrakt: Ticks are a widely distributed arthropod of veterinary importance. Resistance of ticks to synthetic acaricides has become widespread, warranting the development of new drugs for tick management. Carvacrol is a volatile monoterpene, with promising results against various species of ticks; however, to be used for therapeutic purposes, carvacrol must be included in a formulation that makes its application feasible. This study aims to develop a formulation of a carvacrol-containing shampoo that is effective against two species of ticks: Rhipicephalus sanguineus and R. microplus. Shampoo sensory characteristics and pH were evaluated at 37, 25 and 5 °C, for a maximum of 15 days. The shampoo remained stable at 25 and 5 °C. The efficacy of the carvacrol-containing formulation against two species of ticks was assessed by the larval immersion test. Mortality of both tick species was significantly higher for the carvacrol shampoo than for a carvacrol hydroalcoholic solution. In conclusion, the carvacrol-containing shampoo showed larvicidal efficacy on ticks.
Competing Interests: Declaration of competing interest The authors declare no conflict of interest related to this work.
(Copyright © 2022 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: