Chemical composition and bioactivities of Magnolia candollii H.Keng essential oil.

Autor:	Hakim Yahaya AA; Department of Chemistry, Faculty of Science and Mathematics, Universiti Pendidikan Sultan Idris, 35900 Tanjong Malim, Perak, Malaysia., Nuzul Hakimi Wan Salleh WM; Department of Chemistry, Faculty of Science and Mathematics, Universiti Pendidikan Sultan Idris, 35900 Tanjong Malim, Perak, Malaysia.; Fraser's Hill Research Center, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor, Malaysia., Ghani NA; Atta-ur-Rahman Institute for Natural Product Discovery (AuRIns), Universiti Teknologi MARA, Puncak Alam Campus, Level 9, FF3 Building, 42300 Bandar Puncak Alam, Selangor, Malaysia.; Faculty of Applied Sciences, Universiti Teknologi MARA, 40450 Shah Alam, Selangor, Malaysia., Khamis S; Fraser's Hill Research Center, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor, Malaysia.; Department of Biological Sciences and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor, Malaysia., Rezali NS; Chemical Sciences Programme, School of Distance Education, Universiti Sains Malaysia, 11800 Penang, Malaysia., Aizat Juhari MA; Fraser's Hill Research Center, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor, Malaysia.
Jazyk:	angličtina
Zdroj:	Zeitschrift fur Naturforschung. C, Journal of biosciences [Z Naturforsch C J Biosci] 2022 Aug 29; Vol. 77 (11-12), pp. 519-523. Date of Electronic Publication: 2022 Aug 29 (Print Publication: 2022).
DOI:	10.1515/znc-2022-0100
Abstrakt:	Several Magnolia species have exhibited potent biological activities such as anti-inflammatory, anti-angiogenesis, anticonvulsant, anti-obesity, and antiviral activities. However, the Magnolia candollii from Malaysia has not been investigated yet. Hence, this study aims to investigate the chemical composition and bioactivities of the essential oil of Magnolia candollii H.Keng from Malaysia. The hydrodistillation process was used to produce the essential oil, and gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS) were used to analyse it. In total, 44 chemical components were identified in the bark oil, accounting for 98.4%. The major components of the essential oil were α-pinene (29.7%), elemol (10.2%), β-pinene (8.5%), β-caryophyllene (7.2%), α-terpineol (7.0%), guaiol (5.4%), and bulnesol (4.9%). Acetylcholinesterase and anti-inflammatory activities were also evaluated using the Ellman method and lipoxygenase enzyme, respectively, in which the essential oil showed moderate inhibitory activity against acetylcholinesterase (I%: 70.2%) and lipoxygenase (I%: 72.5%). Thus, the findings may be helpful for identifying the medicinal and therapeutic uses of the essential oil from the Magnolia genus. (© 2022 Walter de Gruyter GmbH, Berlin/Boston.)
Databáze:	MEDLINE
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