| Autor: |
Sirangelo TM; CREA-Council for Agricultural Research and Agricultural Economy Analysis, Genomics and Bioinformatics Department, 26836 Montanaso Lombardo, Italy., Ludlow RA; School of Biosciences, Cardiff University, Sir Martin Evans Building, Museum Avenue, Cardiff CF10 3AX, UK., Spadafora ND; Department of Chemical, Pharmaceutical and Agricultural Sciences, University of Ferrara, 44121 Ferrara, Italy. |
| Jazyk: |
angličtina |
| Zdroj: |
Plants (Basel, Switzerland) [Plants (Basel)] 2022 Aug 22; Vol. 11 (16). Date of Electronic Publication: 2022 Aug 22. |
| DOI: |
10.3390/plants11162182 |
| Abstrakt: |
Cannabis ( Cannabis sativa L.), also known as hemp, is one of the oldest cultivated crops, grown for both its use in textile and cordage production, and its unique chemical properties. However, due to the legislation regulating cannabis cultivation, it is not a well characterized crop, especially regarding molecular and genetic pathways. Only recently have regulations begun to ease enough to allow more widespread cannabis research, which, coupled with the availability of cannabis genome sequences, is fuelling the interest of the scientific community. In this review, we provide a summary of cannabis molecular resources focusing on the most recent and relevant genomics, transcriptomics and metabolomics approaches and investigations. Multi-omics methods are discussed, with this combined approach being a powerful tool to identify correlations between biological processes and metabolic pathways across diverse omics layers, and to better elucidate the relationships between cannabis sub-species. The correlations between genotypes and phenotypes, as well as novel metabolites with therapeutic potential are also explored in the context of cannabis breeding programs. However, further studies are needed to fully elucidate the complex metabolomic matrix of this crop. For this reason, some key points for future research activities are discussed, relying on multi-omics approaches. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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