An Overview on Immunogenic Cell Death in Cancer Biology and Therapy.

Autor:	Rodrigues MC; Faculty of Ceilandia, University of Brasilia, Brasilia 72220-275, Brazil.; Laboratory of Nanobiotechnology, Department of Genetics and Morphology, Institute of Biological Sciences, University of Brasilia, Brasilia 70910-900, Brazil., Morais JAV; Faculty of Ceilandia, University of Brasilia, Brasilia 72220-275, Brazil.; Laboratory of Nanobiotechnology, Department of Genetics and Morphology, Institute of Biological Sciences, University of Brasilia, Brasilia 70910-900, Brazil., Ganassin R; Faculty of Ceilandia, University of Brasilia, Brasilia 72220-275, Brazil.; Laboratory of Nanobiotechnology, Department of Genetics and Morphology, Institute of Biological Sciences, University of Brasilia, Brasilia 70910-900, Brazil., Oliveira GRT; Faculty of Ceilandia, University of Brasilia, Brasilia 72220-275, Brazil.; Laboratory of Nanobiotechnology, Department of Genetics and Morphology, Institute of Biological Sciences, University of Brasilia, Brasilia 70910-900, Brazil., Costa FC; Faculty of Ceilandia, University of Brasilia, Brasilia 72220-275, Brazil.; Laboratory of Nanobiotechnology, Department of Genetics and Morphology, Institute of Biological Sciences, University of Brasilia, Brasilia 70910-900, Brazil., Morais AAC; Laboratory of Nanobiotechnology, Department of Genetics and Morphology, Institute of Biological Sciences, University of Brasilia, Brasilia 70910-900, Brazil., Silveira AP; Laboratory of Nanobiotechnology, Department of Genetics and Morphology, Institute of Biological Sciences, University of Brasilia, Brasilia 70910-900, Brazil., Silva VCM; Laboratory of Nanobiotechnology, Department of Genetics and Morphology, Institute of Biological Sciences, University of Brasilia, Brasilia 70910-900, Brazil., Longo JPF; Laboratory of Nanobiotechnology, Department of Genetics and Morphology, Institute of Biological Sciences, University of Brasilia, Brasilia 70910-900, Brazil., Muehlmann LA; Faculty of Ceilandia, University of Brasilia, Brasilia 72220-275, Brazil.; Laboratory of Nanobiotechnology, Department of Genetics and Morphology, Institute of Biological Sciences, University of Brasilia, Brasilia 70910-900, Brazil.
Jazyk:	angličtina
Zdroj:	Pharmaceutics [Pharmaceutics] 2022 Jul 27; Vol. 14 (8). Date of Electronic Publication: 2022 Jul 27.
DOI:	10.3390/pharmaceutics14081564
Abstrakt:	Immunogenic cell death (ICD) is a modality of regulated cell death that is sufficient to promote an adaptive immune response against antigens of the dying cell in an immunocompetent host. An important characteristic of ICD is the release and exposure of damage-associated molecular patterns, which are potent endogenous immune adjuvants. As the induction of ICD can be achieved with conventional cytotoxic agents, it represents a potential approach for the immunotherapy of cancer. Here, different aspects of ICD in cancer biology and treatment are reviewed.
Databáze:	MEDLINE
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