Maternal Early-Life Risk Factors and Later Gestational Diabetes Mellitus: A Cross-Sectional Analysis of the UAE Healthy Future Study (UAEHFS).

Autor:	Juber NF; Public Health Research Center, New York University Abu Dhabi, Abu Dhabi P.O. Box 129188, United Arab Emirates., Abdulle A; Public Health Research Center, New York University Abu Dhabi, Abu Dhabi P.O. Box 129188, United Arab Emirates., AlJunaibi A; Department of Pediatrics, Zayed Military Hospital, Abu Dhabi P.O. Box 72763, United Arab Emirates., AlNaeemi A; Department of Cardiology, Zayed Military Hospital, Abu Dhabi P.O. Box 72763, United Arab Emirates., Ahmad A; Public Health Research Center, New York University Abu Dhabi, Abu Dhabi P.O. Box 129188, United Arab Emirates., Leinberger-Jabari A; Public Health Research Center, New York University Abu Dhabi, Abu Dhabi P.O. Box 129188, United Arab Emirates., Al Dhaheri AS; Department of Nutrition and Health, College of Medicine and Health Sciences, UAE University, Al-Ain P.O. Box 15551, United Arab Emirates., AlZaabi E; Department of Pathology, Sheikh Shakhbout Medical City, Abu Dhabi P.O. Box 11001, United Arab Emirates., Mezhal F; Public Health Research Center, New York University Abu Dhabi, Abu Dhabi P.O. Box 129188, United Arab Emirates., Al-Maskari F; Institute of Public Health, College of Medicine and Health Sciences, UAE University, Al-Ain P.O. Box 15551, United Arab Emirates.; Zayed Center for Health Sciences, UAE University, Al-Ain P.O. Box 15551, United Arab Emirates., AlAnouti F; College of Natural and Health Sciences, Zayed University, Abu Dhabi P.O. Box 144534, United Arab Emirates., Alsafar H; Center for Biotechnology, Khalifa University of Science and Technology, Abu Dhabi P.O. Box 127788, United Arab Emirates.; Department of Genetics and Molecular Biology, Khalifa University of Science and Technology, Abu Dhabi P.O. Box 127788, United Arab Emirates.; Department of Biomedical Engineering, Khalifa University of Science and Technology, Abu Dhabi P.O. Box 127788, United Arab Emirates., Alkaabi J; Department of Internal Medicine, College of Medicine and Health Sciences, UAE University, Al-Ain P.O. Box 15551, United Arab Emirates., Wareth LA; The National Reference Laboratory, Abu Dhabi P.O. Box 92323, United Arab Emirates., Aljaber M; Healthpoint Hospital, Abu Dhabi P.O. Box 112308, United Arab Emirates., Kazim M; Abu Dhabi Blood Bank Services, SEHA, Abu Dhabi P.O. Box 109090, United Arab Emirates., Weitzman M; Department of Environmental Medicine, New York University of Medicine, New York, NY 10016, USA., Al-Houqani M; Department of Medicine, College of Medicine and Health Sciences, UAE University, Al-Ain P.O. Box 15551, United Arab Emirates., Ali MH; Faculty of Health Sciences, Higher Colleges of Technology, Abu Dhabi P.O. Box 25026, United Arab Emirates., Oumeziane N; Abu Dhabi Blood Bank Services, SEHA, Abu Dhabi P.O. Box 109090, United Arab Emirates., El-Shahawy O; Department of Population Health, New York University School of Medicine, New York, NY 10016, USA., Sherman S; Department of Population Health, New York University School of Medicine, New York, NY 10016, USA., AlBlooshi S; College of Natural and Health Sciences, Zayed University, Dubai P.O. Box 19282, United Arab Emirates., Shah SM; Institute of Public Health, College of Medicine and Health Sciences, UAE University, Al-Ain P.O. Box 15551, United Arab Emirates., Loney T; College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai P.O. Box 505055, United Arab Emirates., Almahmeed W; Heart and Vascular Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi P.O. Box 112412, United Arab Emirates., Idaghdour Y; Public Health Research Center, New York University Abu Dhabi, Abu Dhabi P.O. Box 129188, United Arab Emirates., Ali R; Public Health Research Center, New York University Abu Dhabi, Abu Dhabi P.O. Box 129188, United Arab Emirates.; MRC Epidemiology Unit, University of Cambridge, Cambridge CB2 1TN, UK.
Jazyk:	angličtina
Zdroj:	International journal of environmental research and public health [Int J Environ Res Public Health] 2022 Aug 19; Vol. 19 (16). Date of Electronic Publication: 2022 Aug 19.
DOI:	10.3390/ijerph191610339
Abstrakt:	Limited studies have focused on maternal early-life risk factors and the later development of gestational diabetes mellitus (GDM). We aimed to estimate the GDM prevalence and examine the associations of maternal early-life risk factors, namely: maternal birthweight, parental smoking at birth, childhood urbanicity, ever-breastfed, parental education attainment, parental history of diabetes, childhood overall health, childhood body size, and childhood height, with later GDM. This was a retrospective cross-sectional study using the UAE Healthy Future Study (UAEHFS) baseline data (February 2016 to April 2022) on 702 ever-married women aged 18 to 67 years. We fitted a Poisson regression to estimate the risk ratio (RR) for later GDM and its 95% confidence interval (CI). The GDM prevalence was 5.1%. In the fully adjusted model, females with low birthweight were four times more likely (RR 4.04, 95% CI 1.36-12.0) and females with a parental history of diabetes were nearly three times more likely (RR 2.86, 95% CI 1.10-7.43) to report later GDM. In conclusion, maternal birthweight and parental history of diabetes were significantly associated with later GDM. Close glucose monitoring during pregnancy among females with either a low birth weight and/or parental history of diabetes might help to prevent GDM among this high-risk group.
Databáze:	MEDLINE
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