Gonococci resistant to current antimicrobial management standards: a new threat to global public health.

Autor: Dos Santos TF; Anhanguera University, UNIDERP, Campo Grande, Brazil., Goveia MR; Anhanguera University, UNIDERP, Campo Grande, Brazil., Moraes GM; Anhanguera University, UNIDERP, Campo Grande, Brazil., Tavares MA; Federal University of Mato Grosso do Sul, UFMS, Campo Grande, Brazil., Davalos SR; Federal University of Mato Grosso do Sul, UFMS, Campo Grande, Brazil., Campos CB; Anhanguera University, UNIDERP, Campo Grande, Brazil., de Oliveira FA; Federal University of Mato Grosso, UFMT, Cuiabá, Brazil., Benitez DF; Federal University of Mato Grosso, UFMT, Cuiabá, Brazil., Tavares MB; Anhanguera University, UNIDERP, Campo Grande, Brazil., Colli EH; Anhanguera University, UNIDERP, Campo Grande, Brazil., Pinheiro ME; Anhanguera University, UNIDERP, Campo Grande, Brazil., Rodrigues BDR; Anhanguera University, UNIDERP, Campo Grande, Brazil., Neto CD; Anhanguera University, UNIDERP, Campo Grande, Brazil., Ribeiro RS; Anhanguera University, UNIDERP, Campo Grande, Brazil.
Jazyk: angličtina
Zdroj: Future microbiology [Future Microbiol] 2022 Oct; Vol. 17, pp. 1241-1247. Date of Electronic Publication: 2022 Aug 25.
DOI: 10.2217/fmb-2022-0110
Abstrakt: Gonorrhea is the second most common sexually transmitted bacterial infection on the planet and is caused by a Gram-negative cocco, Neisseria gonorrhoeae . Currently, the preferred regimen for the management of this disease in Brazil is a combination of antimicrobials, in this case, ceftriaxone and azithromycin. However, over time, the gonococcus developed a decrease in susceptibility to the regimen used, which resulted in frank resistance to antimicrobials, progressively reducing the therapeutic options available. Thus, the study presented here aims to analyze and discuss the current scenario of resistance of N. gonorrhoeae  to the antimicrobials used to date, to encourage discussion on the subject in the academic environment. For this purpose, 47 articles indexed in the Bireme, PubMed, Scielo and UpToDate platforms were selected.
Databáze: MEDLINE