Sickle Cell Disease Presenting as Extradural Hematoma: An Extremely Rare Fatal Crisis.
| Autor: | Shah D; Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Wardha, IND., Reddy H; Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Wardha, IND., Kumar S; Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Wardha, IND., Acharya S; Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Wardha, IND. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2022 Jul 19; Vol. 14 (7), pp. e27004. Date of Electronic Publication: 2022 Jul 19 (Print Publication: 2022). |
| DOI: | 10.7759/cureus.27004 |
| Abstrakt: | Sickle cell disease (SCD) is due to a gene mutation in the hemoglobin subunit beta gene, whose polymerization when deoxygenated disrupts the physicochemical properties of red blood cells, triggering pan-cellular activation and pathogenic processes such as hemolysis, vaso-occlusion, and ischemia-reperfusion, culminating in the disease's numerous and severe complication like hemorrhage. This case report highlights spontaneous extradural hematoma in a young adult with SCD as an acute neurological complication. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2022, Shah et al.) |
| Databáze: | MEDLINE |
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