Bloodstream infection by Rhodococcus corynebacterioides in a pediatric patient diagnosed with high-risk retinoblastoma.

Autor: Méndez-Cruz AR; Hospital Infantil Teletón de Oncología, Querétaro, Mexico. Electronic address: am54078@gmail.org.mx., Félix-Bermúdez GE; Hospital Infantil Teletón de Oncología, Querétaro, Mexico., Aguilar-Escobar DV; Hospital Infantil Teletón de Oncología, Querétaro, Mexico., Vega-Vega L; Hospital Infantil Teletón de Oncología, Querétaro, Mexico., Morales-Estrada AI; Departamento de Ciencias de la Salud, Universidad del Valle de México, Ciudad de México, México., Contreras-Rodríguez A; Departamento de Microbiología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Ciudad de México, Mexico.
Jazyk: angličtina
Zdroj: Revista Argentina de microbiologia [Rev Argent Microbiol] 2023 Jan-Mar; Vol. 55 (1), pp. 68-72. Date of Electronic Publication: 2022 Aug 18.
DOI: 10.1016/j.ram.2022.06.001
Abstrakt: Rhodococcus is a pathogen that is known to cause infections in animals and humans, mainly in cases of immunocompromised patients. A case of a pediatric cancer patient suffering from a bloodstream infection caused by Rhodococcus corynebacterioides was described in this work. Gram positive rods were isolated from blood cultures. The target bacterium was identified using a combination of biochemical tests, the MALDI-TOF mass spectrometry technique, and the analysis of the 16S rRNA sequence. Moreover, an antimicrobial susceptibility test was performed using the E-test. The isolated bacterium was identified as R. corynebacterioides. The 3-year-old patient was successfully treated with vancomycin and meropenem. This is the first published report of R. corynebacterioides in a pediatric patient diagnosed with retinoblastoma that developed a bloodstream infection. R. corynebacterioides should be considered among the opportunistic infectious agents affecting pediatric cancer patients.
(Copyright © 2022 Asociación Argentina de Microbiología. Publicado por Elsevier España, S.L.U. All rights reserved.)
Databáze: MEDLINE