The impact of fall-related loading rate on the formation of micro-damage in human cortical bone fracture.

Autor: Dapaah D; University of Waterloo, Department of Systems Design Engineering, Canada., Martel DR; University of Waterloo, Department of Kinesiology and Health Sciences, Canada., Laing AC; University of Waterloo, Department of Kinesiology and Health Sciences, Canada., Willett TL; University of Waterloo, Department of Systems Design Engineering, Canada. Electronic address: thomas.willett@uwaterloo.ca.
Jazyk: angličtina
Zdroj: Journal of biomechanics [J Biomech] 2022 Sep; Vol. 142, pp. 111254. Date of Electronic Publication: 2022 Aug 10.
DOI: 10.1016/j.jbiomech.2022.111254
Abstrakt: The quest for better predictive tools as well as new preventative and therapeutic measures for bone fragility and fracture has highlighted the need for greater mechanistic understanding of the bone fracture process. Cortical bone, the major load bearing part of the bone, employs different toughening mechanisms to either inhibit or slow down crack growth which leads to fracture. Among these toughening mechanisms, is the formation of a micro-damage process zone (MDPZ) around the region of the propagating crack. Investigations into the MDPZ to date have primarily been based on quasi-static or cyclic loading rate experiments which do not necessarily replicate physiological fracture rates. Consequently, the impact of fall-related loading rates on the formation of the micro-damage process zone was investigated comparing these to quasi-static loading rate equivalents. The size of MDPZ was found to be 42% smaller in the high-rate group compared to the quasi-static rate group. The smaller MDPZ size was associated with a brittle, unstable fracture behaviour and an overall smaller fracture resistance measure (J max ). This result points to the possibility of a strain rate hardening mechanism at the heart of micro-damage formation, which is hampered under high loading rates, resulting in lower overall fracture resistance.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2022 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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