Utilization of an Electronic Patient-Reported Outcome Platform to Evaluate the Psychosocial and Quality-of-Life Experience Among a Community Sample of Ovarian Cancer Survivors.

Autor:	Hlubocky FJ; Department of Medicine, Section of Hematology/Oncology, MacLean Center for Clinical Medical Ethics, Cancer Research Center, Supportive Oncology Program, The University of Chicago Medicine, Chicago, IL.; Department of Gynecology/Obstetrics, Section of Gynecologic Oncology, The University of Chicago Medicine, Chicago, IL., Daugherty CK; Department of Medicine, Section of Hematology/Oncology, MacLean Center for Clinical Medical Ethics, Cancer Research Center, Supportive Oncology Program, The University of Chicago Medicine, Chicago, IL., Peppercorn J; Division of Medicine, Hematology and Oncology, Dana Farber Partners, Massachusetts General Hospital, Boston, MA., Young K; Illinois Chapter of the National Ovarian Cancer Coalition (NOCC), Chicago, IL., Wroblewski KE; Department of Public Health Sciences, The University of Chicago Medicine, Chicago, IL., Yamada SD; Department of Gynecology/Obstetrics, Section of Gynecologic Oncology, The University of Chicago Medicine, Chicago, IL., Lee NK; Department of Gynecology/Obstetrics, Section of Gynecologic Oncology, The University of Chicago Medicine, Chicago, IL.
Jazyk:	angličtina
Zdroj:	JCO clinical cancer informatics [JCO Clin Cancer Inform] 2022 Aug; Vol. 6, pp. e2200035.
DOI:	10.1200/CCI.22.00035
Abstrakt:	Purpose: Novel distress screening approaches using electronic patient-reported outcome (ePRO) measurements are critical for the provision of comprehensive quality community cancer care. Using an ePRO platform, the prevalence of psychosocial factors (distress, post-traumatic growth, resilience, and financial stress) affecting quality of life in ovarian cancer survivors (OCSs) was examined. Methods: A cross-sectional OCS sample from the National Ovarian Cancer Coalition-Illinois Chapter completed web-based clinical, sociodemographic, and psychosocial assessment using well-validated measures: Hospital Anxiety/Depression Scale-anxiety/depression, Post-traumatic Growth Inventory, Brief Resilience Scale, comprehensive score for financial toxicity, and Functional Assessment of Cancer Therapy-Ovarian (FACT-O/health-related quality of life [HRQOL]). Correlational analyses between variables were conducted. Results: Fifty-eight percent (174 of 300) of OCS completed virtual assessment: median age 59 (range 32-83) years, 94.2% White, 60.3% married/in domestic partnership, 59.6% stage III-IV, 48.8% employed full-time/part-time, 55.2% had college/postgraduate education, 71.9% completed primary treatment, and median disease duration 6 (range < 1-34) years. On average, OCS endorsed normal levels of anxiety (mean ± standard deviation = 6.9 ± 3.8), depression (4.1 ± 3.6), mild total distress (10.9 ± 8.9), high post-traumatic growth (72.6 ± 21.5), normal resilience (3.7 ± 0.72), good FACT-O-HRQOL (112.6 ± 22.8), and mild financial stress (26 ± 10). Poor FACT-O emotional well-being was associated with greater participant distress ( P < .001). Partial correlational analyses revealed negative correlations between FACT-O-HRQOL and anxiety ( r = -0.65, P < .001), depression ( r = -0.76, P < .001), and total distress ( r = -0.92, P < .001). Yet, high FACT-O-HRQOL was positively correlated with post-traumatic coping ( r = 0.27; P = .006) and resilience ( r = 0.63; P < .001). Conclusion: ePRO assessment is feasible for identification of unique psychosocial factors, for example, financial toxicity and resilience, affecting HRQOL for OCS. Future investigation should explore large-scale, longitudinal ePRO assessment of the OCS psychosocial experience using innovative measures and community-based advocacy populations. Competing Interests: Christopher K. DaughertyConsulting or Advisory Role: Daiichi Sankyo, Sun Pharma Jeffery PeppercornEmployment: GlaxoSmithKline (I)Stock and Other Ownership Interests: GlaxoSmithKline (I)Consulting or Advisory Role: Athenex, Abbott LaboratoriesResearch Funding: Outcomes4Me Seiko Diane YamadaOther Relationship: American Board of Obstetrics and Gynecology, ElsevierNo other potential conflicts of interest were reported.
Databáze:	MEDLINE
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