A rare case of sphenoid giant cell tumor: Case report & review of imaging features post short-term denosumab treatment.

Autor:	Aassouani F; Department of Radiology and Interventional Imaging, CHU Hassan II, FEZ, Sidi Mohammed Ben Abdellah University, Morocco., El Bouardi N; Department of Radiology and Interventional Imaging, CHU Hassan II, FEZ, Sidi Mohammed Ben Abdellah University, Morocco., Charifi Y; Department of Radiology and Interventional Imaging, CHU Hassan II, FEZ, Sidi Mohammed Ben Abdellah University, Morocco., Maadin K; Department of Medical Oncology, Oncology Hospital, Morocco., Bouziane A; Department of Radiotherapy, Oncology Hospital, CHU Hassan II, FEZ, Sidi Mohammed Ben Abdellah University, Morocco., Haloua M; Department of Radiology and Interventional Imaging, CHU Hassan II, FEZ, Sidi Mohammed Ben Abdellah University, Morocco., Lamrani MYA; Department of Radiology and Interventional Imaging, CHU Hassan II, FEZ, Sidi Mohammed Ben Abdellah University, Morocco., Arifi S; Department of Medical Oncology, Oncology Hospital, Morocco., Bouhafa T; Department of Radiotherapy, Oncology Hospital, CHU Hassan II, FEZ, Sidi Mohammed Ben Abdellah University, Morocco., Boubbou M; Department of Radiology and Interventional Imaging, CHU Hassan II, FEZ, Sidi Mohammed Ben Abdellah University, Morocco., Maaroufi M; Department of Radiology and Interventional Imaging, CHU Hassan II, FEZ, Sidi Mohammed Ben Abdellah University, Morocco., Alami B; Department of Radiology and Interventional Imaging, CHU Hassan II, FEZ, Sidi Mohammed Ben Abdellah University, Morocco.
Jazyk:	angličtina
Zdroj:	Radiology case reports [Radiol Case Rep] 2022 Aug 09; Vol. 17 (10), pp. 3830-3834. Date of Electronic Publication: 2022 Aug 09 (Print Publication: 2022).
DOI:	10.1016/j.radcr.2022.07.040
Abstrakt:	Background: Giant cell tumors (GCTs) are locally aggressive but rarely malignant bone neoplasms that uncommonly involve the skull. In this report, we describe a tumor of the sphenoid sinus. Case presentation: A 51-year-old female was presented with headache, and bilateral decreased visual acuity, CT scan, and brain MRI revealed an infra-sellar enhancing tumor expanding to the sellar and supra-sellar region which proved to be a GCT. the patient had received 03 months of preoperative denosumab-based treatment and imaging follow-up showed regression in size and morphology modifications of tumor tissue. Conclusion : This is one of few reports to describe the appearance of sphenoid bone GCT, and the first report to highlight the effects of short-term denosumab treatment in GCTb in such a location. (© 2022 The Authors. Published by Elsevier Inc. on behalf of University of Washington.)
Databáze:	MEDLINE
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