Ambient temperature and hospital admissions for non-ST segment elevation myocardial infarction in the tropics.
| Autor: | Seah A; Environmental Epidemiology and Toxicology Division, National Environment Agency, 40 Scotts Road, Environment Building, #13-00, 228231, Singapore. Electronic address: annabel_seah@nea.gov.sg., Ho AFW; Department of Emergency Medicine, Singapore General Hospital, Block 1, Outram Road, Level 3, 169608, Singapore., Soh S; Environmental Epidemiology and Toxicology Division, National Environment Agency, 40 Scotts Road, Environment Building, #13-00, 228231, Singapore. Electronic address: stacy_soh@nea.gov.sg., Zheng H; National Registry of Diseases Office, Health Promotion Board, 3 Second Hospital Avenue, Level 5, 168937, Singapore. Electronic address: ZHENG_Huili@hpb.gov.sg., Pek PP; Pre-hospital & Emergency Research Centre, Duke-NUS Medical School, 8 College Road, 169857, Singapore. Electronic address: maeve.pek@duke-nus.edu.sg., Morgan GG; University Centre for Rural Health, School of Public Health, University of Sydney, PO Box 3074, Lismore, New South Wales 2480, Australia. Electronic address: geoffrey.morgan@sydney.edu.au., Ong MEH; Department of Emergency Medicine, Singapore General Hospital, Block 1, Outram Road, Level 3, 169608, Singapore; Pre-hospital & Emergency Research Centre, Duke-NUS Medical School, 8 College Road, 169857, Singapore. Electronic address: marcus.ong@duke-nus.edu.sg., Aik J; Environmental Epidemiology and Toxicology Division, National Environment Agency, 40 Scotts Road, Environment Building, #13-00, 228231, Singapore; Pre-hospital & Emergency Research Centre, Duke-NUS Medical School, 8 College Road, 169857, Singapore. Electronic address: joel_aik@nea.gov.sg. |
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| Jazyk: | angličtina |
| Zdroj: | The Science of the total environment [Sci Total Environ] 2022 Dec 01; Vol. 850, pp. 158010. Date of Electronic Publication: 2022 Aug 15. |
| DOI: | 10.1016/j.scitotenv.2022.158010 |
| Abstrakt: | Background: Myocardial infarction is an important cause of cardiovascular mortality and can be precipitated by climatic factors. The temperature dependence of myocardial infarction risk has been well examined in temperate settings. Fewer studies have investigated this in the tropics where thermal amplitudes are narrower. This study investigated how ambient temperature influenced the risk of non-ST segment elevation myocardial infarction (NSTEMI), an increasingly common type of myocardial infarction, in the tropical city-state of Singapore. Methods: All nationally reported NSTEMI cases from 2009 to 2018 were included and assessed for its short-term association with ambient temperature using conditional Poisson regression models that comprised a three-way interaction term with year, month and day of the week and adjusted for relative humidity. The Distributed Lag Non-Linear Modelling (DLNM) was used to account for the immediate and lagged effects of environmental exposures. Stratified analysis by sex and age groups was undertaken to assess potential effect modification. Results: There were 60,643 reports of NSTEMI. Temperature decline (cool effect) was associated with a delayed cumulative, non-linear increase in NSTEMI risk over 10 days post exposure [Relative Risk (RR Conclusion: Short-term temperature fluctuations were independently associated with NSTEMI incidence in the tropics, with age as a potential effect modifier of this association. An increase in the frequency of climate change driven temperature events may trigger more instances of NSTEMI in tropical cosmopolitan cities. Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (Copyright © 2022 The Authors. Published by Elsevier B.V. All rights reserved.) |
| Databáze: | MEDLINE |
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