| Autor: |
Mendes LA; Departament of Chemistry, Universidade Federal de Viçosa, Viçosa, Brazil., Silva RRA; Departament of Food Technology, Universidade Federal de Viçosa, Viçosa, Brazil., Soares NFF; Departament of Food Technology, Universidade Federal de Viçosa, Viçosa, Brazil., Martins GF; Departament of General Biology, Universidade Federal de Viçosa, Viçosa, Brazil., Teixeira RR; Departament of Chemistry, Universidade Federal de Viçosa, Viçosa, Brazil., da Silva Ferreira MF; Departament of Agronomy, Universidade Federal do Espírito Santo, Alegre, Brazil., Moreira RPL; Departament of Chemistry, Universidade Federal de Viçosa, Viçosa, Brazil. |
| Abstrakt: |
Inclusion complexes (ICs) of 2-hydroxypropyl-β-cyclodextrin with the essential oil (EO) from Seculo XXI cultivar of Psidium guajava were prepared using kneading (KN) and freeze-drying (FD) methods. The resulting ICs clusters have a nanometric size, with a diameter of approximately 80 and 40 nm for KN and FD, respectively. Complexation efficiency was 80.3% and 50.8% for KN and FD methods, respectively. The larvicidal activity of the EO in DMSO on A. aegypti had LC 50 and LC 90 values of 51.49 and 64.51 µg mL -1 , respectively. For the KN method, the toxicity corresponded to 77.54 and 107.29 µg mL -1 for LC 50 and LC 90 , respectively. FD method demonstrated toxicity at concentrations above 600 µg mL -1 . Thus, ICs enable the use of EO in breeding sites for A. aegypti , thus being potential products to be commercially exploited. |
