Primary signet-ring cell carcinoma of the cecum: A rare case report.

Autor:	Anas D; Department of General Surgery, Mohamed VI University Hospital, Oujda, Morocco; Faculty of Medicine and Pharmacy, Laboratory of Anatomy, Microsurgery and Surgery Experimental and Medical Simulation (LAMCESM), Mohammed 1st University, Oujda, Morocco. Electronic address: Anas.derkaoui.95@gmail.com., Tarik D; Department of General Surgery, Mohamed VI University Hospital, Oujda, Morocco; Faculty of Medicine and Pharmacy, Laboratory of Anatomy, Microsurgery and Surgery Experimental and Medical Simulation (LAMCESM), Mohammed 1st University, Oujda, Morocco., Yassine MM; Department of General Surgery, Mohamed VI University Hospital, Oujda, Morocco; Faculty of Medicine and Pharmacy, Laboratory of Anatomy, Microsurgery and Surgery Experimental and Medical Simulation (LAMCESM), Mohammed 1st University, Oujda, Morocco., Haitam S; Department of General Surgery, Mohamed VI University Hospital, Oujda, Morocco; Faculty of Medicine and Pharmacy, Laboratory of Anatomy, Microsurgery and Surgery Experimental and Medical Simulation (LAMCESM), Mohammed 1st University, Oujda, Morocco., Ayoub M; Department of General Surgery, Mohamed VI University Hospital, Oujda, Morocco; Faculty of Medicine and Pharmacy, Laboratory of Anatomy, Microsurgery and Surgery Experimental and Medical Simulation (LAMCESM), Mohammed 1st University, Oujda, Morocco., Magouri O; Department of Pathology, Mohammed VI University Hospital, Oujda, Morocco., Rachid J; Department of General Surgery, Mohamed VI University Hospital, Oujda, Morocco; Faculty of Medicine and Pharmacy, Laboratory of Anatomy, Microsurgery and Surgery Experimental and Medical Simulation (LAMCESM), Mohammed 1st University, Oujda, Morocco., Mohammed B; Department of General Surgery, Mohamed VI University Hospital, Oujda, Morocco; Faculty of Medicine and Pharmacy, Laboratory of Anatomy, Microsurgery and Surgery Experimental and Medical Simulation (LAMCESM), Mohammed 1st University, Oujda, Morocco.
Jazyk:	angličtina
Zdroj:	International journal of surgery case reports [Int J Surg Case Rep] 2022 Sep; Vol. 98, pp. 107466. Date of Electronic Publication: 2022 Jul 30.
DOI:	10.1016/j.ijscr.2022.107466
Abstrakt:	Introduction and Importance: Primary SRCC is a rare histological colorectal cancer subtype. It is characterized by distinct clinical presentation. Case Presentation: This case report describes a rare case of a Primary Signet-ring cell carcinoma of the cecum. A 37-year-old man came to the emergency department with bowel obstruction and altered general condition. The abdominal CT scan showed an intestinal occlusion upstream a thickening of the cecum. An exploratory laparotomy found a distention of the bowl with a suspect thickening of the cecum. The patient underwent a right ileo-colectomy and ileocolostomy. Histologic analysis of the operatory specimen confirmed the diagnosis of a primary Signet-ring cell carcinoma of the cecum. The recovery was uneventful, and the patient is in good health after six -months of follow-up. After completing the chemotherapy, the patient is scheduled for a colonoscopy and reversal of colostomy. Clinical Discussion: Colorectal primary signet ring cell carcinoma (SRCC) is a rare entity, and it is associated with poor prognosis compared with common colorectal adenocarcinomas. characterized by distinct clinical presentation, with very poor response rates. Conclusion: Primary SRCC is an aggressive histological type of colon cancer and it is associated with a poor prognosis. There are no conclusive guidelines for the treatment of this type of tumor. Competing Interests: Declaration of competing interest There are no conflicts of interest with respect to research, authorship and/or publication of the article. (Copyright © 2022 The Authors. Published by Elsevier Ltd.. All rights reserved.)
Databáze:	MEDLINE
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