Visual-stress-related cortical excitability as a prospective marker for symptoms of depression and anxiety in young people.

Autor: Hui CL; Department of Psychiatry, School of Clinical Medicine, Faculty of Medicine, Li Ka Shing, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong SAR, China., Wong SM; Department of Psychiatry, School of Clinical Medicine, Faculty of Medicine, Li Ka Shing, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong SAR, China., Yu TY; Department of Psychiatry, School of Clinical Medicine, Faculty of Medicine, Li Ka Shing, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong SAR, China., Lau TT; Department of Psychiatry, School of Clinical Medicine, Faculty of Medicine, Li Ka Shing, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong SAR, China., Choi O; Department of Psychiatry, School of Clinical Medicine, Faculty of Medicine, Li Ka Shing, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong SAR, China., Tsang S; Department of Psychiatry, School of Clinical Medicine, Faculty of Medicine, Li Ka Shing, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong SAR, China., Suen YN; Department of Psychiatry, School of Clinical Medicine, Faculty of Medicine, Li Ka Shing, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong SAR, China., Lam BY; Department of Psychiatry, School of Clinical Medicine, Faculty of Medicine, Li Ka Shing, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong SAR, China., Wong CS; Department of Psychiatry, School of Clinical Medicine, Faculty of Medicine, Li Ka Shing, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong SAR, China., Lui SS; Department of Psychiatry, School of Clinical Medicine, Faculty of Medicine, Li Ka Shing, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong SAR, China., Chan KT; Department of Psychiatry, School of Clinical Medicine, Faculty of Medicine, Li Ka Shing, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong SAR, China., Wong MT; Department of Psychiatry, School of Clinical Medicine, Faculty of Medicine, Li Ka Shing, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong SAR, China., Wong GH; Department of Social Work and Social Administration, The University of Hong Kong, Hong Kong, China., Chan SK; Department of Psychiatry, School of Clinical Medicine, Faculty of Medicine, Li Ka Shing, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong SAR, China.; State Key Laboratory of Brain and Cognitive Sciences, University of Hong Kong, Hong Kong, China., Lee EH; Department of Psychiatry, School of Clinical Medicine, Faculty of Medicine, Li Ka Shing, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong SAR, China., Chang WC; Department of Psychiatry, School of Clinical Medicine, Faculty of Medicine, Li Ka Shing, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong SAR, China.; State Key Laboratory of Brain and Cognitive Sciences, University of Hong Kong, Hong Kong, China., Wilkins A; Department of Psychology, University of Essex, Essex, UK., Chen EY; Department of Psychiatry, School of Clinical Medicine, Faculty of Medicine, Li Ka Shing, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong SAR, China. ericchen.hku@gmail.com.; State Key Laboratory of Brain and Cognitive Sciences, University of Hong Kong, Hong Kong, China. ericchen.hku@gmail.com.
Jazyk: angličtina
Zdroj: European archives of psychiatry and clinical neuroscience [Eur Arch Psychiatry Clin Neurosci] 2023 Aug; Vol. 273 (5), pp. 1051-1060. Date of Electronic Publication: 2022 Aug 16.
DOI: 10.1007/s00406-022-01469-7
Abstrakt: Visual stress is thought to reflect cortical excitability and has been associated with many neurological, neuropsychiatric, and neurodevelopmental conditions. However, its relationships with symptoms of depression and anxiety have not yet been elucidated. We conducted two separate studies to first examine visual stress in a longitudinal community sample of 104 participants (aged 12-24) in association with prospective symptoms of depression, anxiety, and distress after 3 months, and subsequently in a cross-sectional epidemiological sample of 530 participants (aged 15-24) to validate its associations with current mood and distress symptoms. The Pattern Glare Test was used to examine visual stress to three grating patterns with the spatial frequencies (SF) of 0.3, 2.3, and 9.4 cycles per degree (cpd). Other known factors of mental health, including functioning, as well as resilience, hopelessness, and loneliness, were also assessed at baseline. In both studies, we showed that perceptual distortions were highest toward the pattern with mid-SF (2.3 cpd). Multiple linear regression analyses revealed that greater visual stress was significantly associated with not only baseline but also 3-month symptom outcomes, even when accounting for age, years of education, days of no functioning, resilience, hopelessness, and loneliness. Our findings suggest the importance of visual stress in understanding and predicting poor mental health outcomes. As mental health can lead to far-reaching consequences that extend to adulthood, our findings may inform state-of-the-art innovative strategies for the prediction of poor mental health outcomes and suggest visual stress as a potential marker for early risk detection among young people.
(© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany.)
Databáze: MEDLINE
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