Neuroscience from the comfort of your home: Repeated, self-administered wireless dry EEG measures brain function with high fidelity.

Autor:	Barbey FM; School of Psychology, Trinity College Dublin, Dublin, Ireland.; Cumulus Neuroscience Ltd., Dublin, Ireland., Farina FR; School of Psychology, Trinity College Dublin, Dublin, Ireland.; Trinity College Institute of Neuroscience, Dublin, Ireland., Buick AR; Cumulus Neuroscience Ltd., Belfast, United Kingdom., Danyeli L; Department of Psychiatry and Psychotherapy, Jena University Hospital, Jena, Germany.; Department of Behavioral Neurology, Leibniz Institute for Neurobiology, Magdeburg, Germany.; Clinical Affective Neuroimaging Laboratory, Magdeburg, Germany., Dyer JF; Cumulus Neuroscience Ltd., Belfast, United Kingdom., Islam MN; Cumulus Neuroscience Ltd., Dublin, Ireland., Krylova M; Department of Psychiatry and Psychotherapy, Jena University Hospital, Jena, Germany.; Clinical Affective Neuroimaging Laboratory, Magdeburg, Germany.; Medical Physics Group, Institute of Diagnostic and Interventional Radiology, Jena University Hospital, Jena, Germany., Murphy B; Cumulus Neuroscience Ltd., Dublin, Ireland., Nolan H; Cumulus Neuroscience Ltd., Dublin, Ireland., Rueda-Delgado LM; Cumulus Neuroscience Ltd., Dublin, Ireland.; Trinity Centre for Biomedical Engineering, Trinity College Dublin, Dublin, Ireland., Walter M; Department of Psychiatry and Psychotherapy, Jena University Hospital, Jena, Germany.; Department of Behavioral Neurology, Leibniz Institute for Neurobiology, Magdeburg, Germany.; Clinical Affective Neuroimaging Laboratory, Magdeburg, Germany.; Department of Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany.; Medical Faculty, Otto von Guericke University of Magdeburg, Magdeburg, Germany., Whelan R; School of Psychology, Trinity College Dublin, Dublin, Ireland.; Trinity College Institute of Neuroscience, Dublin, Ireland.
Jazyk:	angličtina
Zdroj:	Frontiers in digital health [Front Digit Health] 2022 Jul 29; Vol. 4, pp. 944753. Date of Electronic Publication: 2022 Jul 29 (Print Publication: 2022).
DOI:	10.3389/fdgth.2022.944753
Abstrakt:	Recent advances have enabled the creation of wireless, "dry" electroencephalography (EEG) recording systems, and easy-to-use engaging tasks, that can be operated repeatedly by naïve users, unsupervised in the home. Here, we evaluated the validity of dry-EEG, cognitive task gamification, and unsupervised home-based recordings used in combination. Two separate cohorts of participants-older and younger adults-collected data at home over several weeks using a wireless dry EEG system interfaced with a tablet for task presentation. Older adults ( n = 50; 25 females; mean age = 67.8 years) collected data over a 6-week period. Younger male adults ( n = 30; mean age = 25.6 years) collected data over a 4-week period. All participants were asked to complete gamified versions of a visual Oddball task and Flanker task 5-7 days per week. Usability of the EEG system was evaluated via participant adherence, percentage of sessions successfully completed, and quantitative feedback using the System Usability Scale. In total, 1,449 EEG sessions from older adults (mean = 28.9; SD = 6.64) and 684 sessions from younger adults (mean = 22.87; SD = 1.92) were collected. Older adults successfully completed 93% of sessions requested and reported a mean usability score of 84.5. Younger adults successfully completed 96% of sessions and reported a mean usability score of 88.3. Characteristic event-related potential (ERP) components-the P300 and error-related negativity-were observed in the Oddball and Flanker tasks, respectively. Using a conservative threshold for inclusion of artifact-free data, 50% of trials were rejected per at-home session. Aggregation of ERPs across sessions (2-4, depending on task) resulted in grand average signal quality with similar Standard Measurement Error values to those of single-session wet EEG data collected by experts in a laboratory setting from a young adult sample. Our results indicate that easy-to-use task-driven EEG can enable large-scale investigations in cognitive neuroscience. In future, this approach may be useful in clinical applications such as screening and tracking of treatment response. Competing Interests: Conflict of interest FB, AB, JD, MI, BM, HN, and LR-D are employees of Cumulus Neuroscience Ltd., a company that develops and provides dry EEG technology. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2022 Barbey, Farina, Buick, Danyeli, Dyer, Islam, Krylova, Murphy, Nolan, Rueda-Delgado, Walter and Whelan.)
Databáze:	MEDLINE
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