Oocyte Cryopreservation in Patients with Endometriosis: Current Knowledge and Number Needed to Treat.

Autor: Henry L; Center for Reproductive Medicine, University of Liège, Boulevard du 12ème de Ligne 1, 4000 Liege, Belgium., Vervier J; Obstetrics and Gynecology Department, University of Liège, Boulevard du 12ème de Ligne 1, 4000 Liege, Belgium., Boucher A; Center for Reproductive Medicine, University of Liège, Boulevard du 12ème de Ligne 1, 4000 Liege, Belgium., Brichant G; Obstetrics and Gynecology Department, University of Liège, Boulevard du 12ème de Ligne 1, 4000 Liege, Belgium., Gaspard O; Center for Reproductive Medicine, University of Liège, Boulevard du 12ème de Ligne 1, 4000 Liege, Belgium., Labied S; Center for Reproductive Medicine, University of Liège, Boulevard du 12ème de Ligne 1, 4000 Liege, Belgium., Munaut C; Laboratory of Tumor and Development Biology, Giga-Cancer, University of Liège, 4000 Liege, Belgium., Ravet S; Center for Reproductive Medicine, University of Liège, Boulevard du 12ème de Ligne 1, 4000 Liege, Belgium., Nisolle M; Obstetrics and Gynecology Department, University of Liège, Boulevard du 12ème de Ligne 1, 4000 Liege, Belgium.
Jazyk: angličtina
Zdroj: Journal of clinical medicine [J Clin Med] 2022 Aug 04; Vol. 11 (15). Date of Electronic Publication: 2022 Aug 04.
DOI: 10.3390/jcm11154559
Abstrakt: The rise of oocytes cryopreservation (OOC) in assisted reproductive techniques allows fertility preservation (FP) in an increasing number of indications. Endometriosis, a highly prevalent disease, potentially impairing ovarian reserve, seems, therefore, an interesting indication for it. The purpose of this study is to summarize the available evidence concerning FP by OOC in women with endometriosis and to calculate the number needed to treat (NNT). In total, 272 articles related to this topic were identified in PubMed. Eight studies were eligible for the review. In order to shed some light, a SWOT analysis was performed and the argument pros and cons were developed. The NNT calculated of OOC was 16, meaning that 16 women need to perform an OOC for one of them to have a child that she would not have had without this technique. In conclusion, OOC must be discussed with patients who suffer from endometriosis since it is an effective technique of FP, which can allow these patients to succeed a pregnancy that they otherwise would not have achieved. Nevertheless, it should not be performed in all patients as there is still a lack of robust socio-economic and risk-benefit data.
Databáze: MEDLINE
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