An International Expert Delphi Consensus on Defining Textbook Outcome in Liver Surgery (TOLS).

Autor:	Görgec B; Department of Surgery, Poliambulanza Foundation Hospital, Brescia, Italy.; Department of Surgery, AmsterdamUMC, University of Amsterdam, Amsterdam, the Netherlands.; Cancer Center Amsterdam, Amsterdam, the Netherlands.; Department of Surgery, University Hospital Southampton NHS Foundation Trust, Southampton, UK., Benedetti Cacciaguerra A; Department of Surgery, Poliambulanza Foundation Hospital, Brescia, Italy.; Department of Surgery, University Hospital Southampton NHS Foundation Trust, Southampton, UK.; Hepatobiliary and Abdominal Transplantation Surgery, Department of Experimental and Clinical Medicine, Riuniti Hospital, Polytechnic University of Marche, Ancona, Italy., Pawlik TM; Division of Surgical Oncology, Department of Surgery, The Ohio State University Wexner Medical Center and James Comprehensive Cancer Center, Columbus, OH., Aldrighetti LA; Hepatobiliary Surgery Division, IRCCS San Raffaele Hospital, Milan, Italy., Alseidi AA; Department of Surgery, University of California San Francisco, San Francisco, CA., Cillo U; Department of Surgery, Oncology and Gastroenterology, Hepatobiliary Surgery and Liver Transplantation Unit, Padova University Hospital, Padova, Italy., Kokudo N; Department of Surgery, Hepatobiliary Pancreatic Surgery Division, National Center for Global Health and Medicine, Tokyo, Japan., Geller DA; Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA., Wakabayashi G; Center for Advanced Treatment of Hepatobiliary and Pancreatic Diseases, Ageo Central General Hospital, Saitama, Japan., Asbun HJ; Hepato-Biliary and Pancreas Surgery, Miami Cancer Institute, Miami, FL., Besselink MG; Department of Surgery, AmsterdamUMC, University of Amsterdam, Amsterdam, the Netherlands.; Cancer Center Amsterdam, Amsterdam, the Netherlands., Cherqui D; Department of Hepatobiliary Surgery, Paul Brousse University Hospital, Villejuif, France., Cheung TT; Department of Surgery, The University of Hong Kong, Hong Kong, China., Clavien PA; Department of surgery and transplantation, University Hospital Zurich, Switzerland., Conrad C; Department of Surgery, St. Elizabeth's Medical Center, Tufts University School of Medicine, Boston, MA., D'Hondt M; Department of Digestive and Hepatobiliary/Pancreatic Surgery, Groeninge Hospital, Kortrijk, Belgium., Dagher I; Department of Minimally Invasive Digestive Surgery, Antoine Béclère Hospital, Clamart, France., Dervenis C; Department of Surgery, Konstantopouleio General Hospital, Nea Ionia, Athens, Greece., Devar J; Department of Surgery, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.; Hepato-Pancreatico-Biliary Unit, Department of General Surgery, Chris Hani Baragwanath Academic Hospital, Johannesburg, South Africa., Dixon E; Department of Surgery, University of Calgary, Calgary, AB, Canada., Edwin B; Department of Hepato-Pancreato-Biliary Surgery and The Intervention Center, Oslo University Hospital Oslo, Oslo, Norway.; Institute of Clinical Medicine, Medical Faculty, University of Oslo, Oslo, Norway., Efanov M; Department of Hepato-Pancreato-Biliary Surgery, Moscow Clinical Research Centre, Moscow, Russia., Ettore GM; General Surgery and Transplantation Unit, San Camillo Hospital, Rome, Italy., Ferrero A; Department of General and Oncological Surgery, Umberto I Mauriziano Hospital, Turin, Italy., Fondevilla C; General & Digestive Surgery, Hospital Universitario La Paz, IdiPAZ, Madrid, Spain., Fuks D; Department of Digestive, Oncologic and Metabolic Surgery, Institut Mutualiste Montsouris, Université Paris Descartes, Paris, France., Giuliante F; Chirurgia Epatobiliare, Università Cattolica del Sacro Cuore-IRCCS, Rome, Italy., Han HS; Department of Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam-si, Gyeonggi-do, Republic of Korea., Honda G; Department of Surgery, Institute of Gastroenterology, Tokyo Women's Medical University, Tokyo, Japan., Imventarza O; Department of surgery, Hospital Argerich, Buenos Aires, Argentina.; Department of surgery, Hospital Garrahan, Buenos Aires, Argentina., Kooby DA; Department of Surgery, Emory University School of Medicine, Winship Cancer Institute, Atlanta, GA., Lodge P; HPB and Transplant Unit, St James's University Hospital, Leeds, UK., Lopez-Ben S; Department of General and Digestive Surgery, HPB Unit, Hospital Universitari de Girona Dr. Josep Trueta, Girona, Spain., Machado MA; Department of Surgery, University of São Paulo, São Paulo, Brazil., Marques HP; Department of Surgery, Curry Cabral Hospital, Lisbon, Portugal., O'Rourke N; Department of HPB Surgery, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia., Pekolj J; Division of HPB Surgery and Liver Transplant Unit, Department of General Surgery, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina., Pinna AD; Abdominal Transplant and HPB Center, Cleveland Clinic Florida, Weston, Florida., Portolani N; Department of Clinical and Experimental Sciences, Surgical Clinic, University of Brescia, Italy., Primrose J; Department of Surgery, University Hospital Southampton NHS Foundation Trust, Southampton, UK., Rotellar F; Department of General and Digestive Surgery, Clinica Universidad de Navarra, Pamplona, Spain., Ruzzenente A; Department of Surgery, University of Verona, Verona, Italy., Schadde E; Institute of Physiology, University of Zurich, Zurich, Switzerland.; Department of Surgery, Cantonal Hospital Winterthur, Zurich, Switzerland.; Division of Transplant Surgery, Department of Surgery, Rush University Medical Center, Chicago, IL., Siriwardena AK; Hepatobiliary and Pancreatic Surgery Unit, Manchester University NHS FT, Manchester, UK., Smadi S; Department of Surgery, King Hussein Medical Center, Amman, Jordan., Soubrane O; Department of Hepatobiliopancreatic Surgery, APHP, Beaujon Hospital, Clichy, France., Tanabe KK; Division of Surgical Oncology, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA., Teh CSC; Section of Hepatobiliary Pancreatic Surgery, Surgical Oncology, and Minimally Invasive Surgery, St Luke's Medical Center, Quezon City, Philippines., Torzilli G; Division of Hepatobiliary and General Surgery, Department of Surgery, Humanitas Clinical and Research Center, IRCCS, Humanitas University, Rozzano, Italy., Van Gulik TM; Department of Surgery, AmsterdamUMC, University of Amsterdam, Amsterdam, the Netherlands.; Cancer Center Amsterdam, Amsterdam, the Netherlands., Vivarelli M; Hepatobiliary and Abdominal Transplantation Surgery, Department of Experimental and Clinical Medicine, Riuniti Hospital, Polytechnic University of Marche, Ancona, Italy., Wigmore SJ; Department of Hepato-Pancreato-Biliary (HPB)/Transplant Surgery, The University of Edinburgh Clinical Surgery, Edinburgh, UK., Abu Hilal M; Department of Surgery, Poliambulanza Foundation Hospital, Brescia, Italy.; Department of Surgery, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
Jazyk:	angličtina
Zdroj:	Annals of surgery [Ann Surg] 2023 May 01; Vol. 277 (5), pp. 821-828. Date of Electronic Publication: 2022 Aug 10.
DOI:	10.1097/SLA.0000000000005668
Abstrakt:	Objective: To reach global expert consensus on the definition of TOLS in minimally invasive and open liver resection among renowned international expert liver surgeons using a modified Delphi method. Background: Textbook outcome is a novel composite measure combining the most desirable postoperative outcomes into one single measure and representing the ideal postoperative course. Despite a recently developed international definition of Textbook Outcome in Liver Surgery (TOLS), a standardized and expert consensus-based definition is lacking. Methods: This international, consensus-based, qualitative study used a Delphi process to achieve consensus on the definition of TOLS. The survey comprised 6 surgical domains with a total of 26 questions on individual surgical outcome variables. The process included 4 rounds of online questionnaires. Consensus was achieved when a threshold of at least 80% agreement was reached. The results from the Delphi rounds were used to establish an international definition of TOLS. Results: In total, 44 expert liver surgeons from 22 countries and all 3 major international hepato-pancreato-biliary associations completed round 1. Forty-two (96%), 41 (98%), and 41 (98%) of the experts participated in round 2, 3, and 4, respectively. The TOLS definition derived from the consensus process included the absence of intraoperative grade ≥2 incidents, postoperative bile leakage grade B/C, postoperative liver failure grade B/C, 90-day major postoperative complications, 90-day readmission due to surgery-related major complications, 90-day/in-hospital mortality, and the presence of R0 resection margin. Conclusions: This is the first study providing an international expert consensus-based definition of TOLS for minimally invasive and open liver resections by the use of a formal Delphi consensus approach. TOLS may be useful in assessing patient-level hospital performance and carrying out international comparisons between centers with different clinical practices to further improve patient outcomes. (Copyright © 2022 The Author(s). Published by Wolters Kluwer Health, Inc.)
Databáze:	MEDLINE
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