Hyperlactatemia and other perioperative metabolic disturbances in neuroanesthesia.

Autor: Klimek M; Department of Anesthesiology, Erasmus University Medical Center, Rotterdam, The Netherlands., de Smalen P, Janssen J
Jazyk: angličtina
Zdroj: Current opinion in anaesthesiology [Curr Opin Anaesthesiol] 2022 Oct 01; Vol. 35 (5), pp. 537-542. Date of Electronic Publication: 2022 Aug 16.
DOI: 10.1097/ACO.0000000000001180
Abstrakt: Purpose of Review: The concept of 'brain-body cross-talking' has gained growing interest in the last years. The understanding of the metabolic disturbances (e.g., hypernatraemia/hyponatraemia and hyperlactatemia) in neurosurgical patients has improved during the last years.
Recent Findings: The impact of elevated lactate without acidosis in neurosurgical patients remains controversial. The pathophysiology of inappropriate secretion of antidiuretic hormone (SIADH) has become clearer, whereas the diagnosis of cerebral salt wasting should be used more carefully.
Summary: These findings will contribute to a better understanding of the pathophysiology involved and enable better prevention and therapy where possible in clinical practice.
(Copyright © 2022 The Author(s). Published by Wolters Kluwer Health, Inc.)
Databáze: MEDLINE