The pathogenesis of Nipah virus: A review.

Autor: Devnath P; Department of Microbiology, Noakhali Science and Technology University, Noakhali, 3814, Bangladesh. Electronic address: popydn.mbg@nstu.edu.bd., Wajed S; Department of Microbiology, Noakhali Science and Technology University, Noakhali, 3814, Bangladesh., Chandra Das R; Department of Microbiology, Noakhali Science and Technology University, Noakhali, 3814, Bangladesh., Kar S; Child Health Research Foundation, Sher-E-Bangla Nagar, Dhaka, 1207, Bangladesh., Islam I; Department of Microbiology, Noakhali Science and Technology University, Noakhali, 3814, Bangladesh., Masud HMAA; Department of Microbiology, Faculty of Biological Sciences, University of Chittagong, Chattogram, 4331, Bangladesh. Electronic address: masud.mbio@cu.ac.bd.
Jazyk: angličtina
Zdroj: Microbial pathogenesis [Microb Pathog] 2022 Sep; Vol. 170, pp. 105693. Date of Electronic Publication: 2022 Aug 06.
DOI: 10.1016/j.micpath.2022.105693
Abstrakt: Nipah virus (NiV), an emerging zoonotic virus, has been associated with several outbreaks with high death rates, mainly in South and Southeast Asia. NiV is responsible for Encephalitis and systemic vasculitis, and occasionally respiratory diseases accompanied by it. Though fruit bats are the natural source of NiV, it can be transmitted in a zoonotic manner directly or via an intermediate host (e.g., a pig or horse). Several studies explore the viral mechanism of disease progressions and its overall pathogenesis. However, understanding the pathogenesis and disease dynamics is necessary to develop therapeutic options and vaccines. Thus, in this review, we provide a comprehensive update on the emerging understanding of the pathogenesis of NiV.
Competing Interests: Declaration of competing interest The authors have no conflict of interest to declare.
(Copyright © 2022 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: