Propofol infusion syndrome & COVID-19 in a victim of multiple gunshot wounds: Diagnostic and therapeutic dilemmas.

Autor: Lew FH; Elson S Floyd College of Medicine at Washington State University, Spokane, WA, United States of America., Chang KM; Elson S Floyd College of Medicine at Washington State University, Spokane, WA, United States of America., Singares ES; Elson S Floyd College of Medicine at Washington State University, Spokane, WA, United States of America.; Trauma & Emergency Surgical Services, Elson S Floyd College of Medicine at Washington State University & Kadlec Medical Center, Richland, WA, United States of America.
Jazyk: angličtina
Zdroj: Trauma case reports [Trauma Case Rep] 2022 Oct; Vol. 41, pp. 100687. Date of Electronic Publication: 2022 Aug 01.
DOI: 10.1016/j.tcr.2022.100687
Abstrakt: Background: COVID-19 has become a global pandemic. It has affected patients the world over, and when minimally symptomatic, it can be an incidental finding in trauma patients. It may also make the diagnosis of other rare conditions more difficult due to clinical finding superimposition.
Case Presentation: A 23-year-old male was transferred to our Trauma Center in hemorrhagic shock after sustaining multiple gunshot wounds in the upper back. Imaging showed a retained projectile in the right pharyngeal area, a right upper lobe contusion, and a right hemopneumothorax; with additional infiltrates on both lungs suggestive of atelectasis. After intubation, a propofol infusion was started for sedation. Shortly thereafter worsening acidosis, refractory hypoxia, and hypotension with additional laboratory anomalies ensued, as the PCR screening for SARS-CoV-2 returned positive. The clinical findings suggested COVID-19 pneumonia with possible superimposed Propofol Infusion Syndrome. The drug was stopped, and the symptoms improved.
Conclusion: A high index of suspicion is necessary to manage unusual pathologies and difficult differential diagnoses, and this is especially true during the ongoing pandemic.
Competing Interests: None of the authors have any competing interests to declare.
(© 2022 The Authors.)
Databáze: MEDLINE