Transcutaneous bilirubin levels in extremely preterm infants less than 30 weeks gestation.

Autor: Sankar MN; Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University, Stanford, CA, USA. mnsankar@stanford.edu., Ramanathan R; Division of Neonatology, LAC + USC Medical Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Joe P; Neonatology, UCSF Benioff Children's Oakland, Oakland, CA, USA., Katheria AC; Neonatal Research Institute, Sharp Mary Birch Hospital for Women and Newborns, San Diego, CA, USA., Villosis MFB; Neonatology, Kaiser Foundation Hospital, Panorama City, CA, USA., Cortes M; Department of Pediatrics/Neonatology, Santa Clara Valley Medical Center, San Jose, CA, USA., Bhatt DR; Neonatology, Kaiser Permanente Fontana Medical Center, Fontana, CA, USA., Truong H; Neonatology, Kaiser Permanente Fontana Medical Center, Fontana, CA, USA., Paje V; Neonatology, Kaiser Permanente Fontana Medical Center, Fontana, CA, USA., Tan RC; Neonatology, Miller Children's Hospital, Long Beach, CA, USA., Arora V; Neonatology, Kaiser Foundation Hospital, Downey, CA, USA., Nguyen M; Neonatology, Kaiser Permanente Southern California Orange County, Anaheim, CA, USA., Biniwale M; Division of Neonatology, LAC + USC Medical Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Jazyk: angličtina
Zdroj: Journal of perinatology : official journal of the California Perinatal Association [J Perinatol] 2023 Feb; Vol. 43 (2), pp. 220-225. Date of Electronic Publication: 2022 Aug 05.
DOI: 10.1038/s41372-022-01477-4
Abstrakt: Objective: The primary objective of this study was to determine the relationship between transcutaneous bilirubin (TcB) levels and total serum bilirubin (TSB) levels in extremely preterm infants.
Study Design: We conducted a prospective multicenter study of extremely preterm infants less than 30 weeks gestation in California. Difference between paired TcB and TSB values were compared based on gestational age, birth weight, maternal race/ethnicity, chronological age as well as during and after phototherapy.
Results: TSB values ranged from 0 to 12.6 mg/dl and the TcB values ranged from 0 to 14.2 mg/dl. TSB was predicted with a high degree of accuracy at TSB = 2.37 + 0.54 (TcB) with r = 0.786. There was good correlation across gestational age, birth weight, race/ethnic, chronological age subgroups as well as during and after phototherapy.
Conclusion: Our study supports the use of TcB as a screening tool for monitoring jaundice in extremely preterm infants.
(© 2022. The Author(s), under exclusive licence to Springer Nature America, Inc.)
Databáze: MEDLINE
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